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Cat.No. Product Name / Introduction Added
CS-3381 Icatibant September 2014
Icatibant(HOE-140) is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.
 
CS-3380 Sivelestat-sodium-tetrahydrate September 2014
Sivelestat(ONO5046; LY544349; EI546) is a competitive inhibitor of human neutrophil elastase(IC50 = 44 nM; Ki=200 nM); also inhibited leukocyte elastase obtained from rabbit, rat, hamster and mouse.
 
CS-3379 UNBS5162 September 2014
UNBS5162 is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers; the mean antiproliferative activity IC50 value is 17.
 
CS-3378 Pimavanserin September 2014
Pimavanserin(ACP-103) is a potent and selective 5-HT2A receptor inverse agonist with mean pIC50 of with 8.
 
CS-3377 PF-1022A September 2014
PF 1022A is a N-methylated cyclooctadepsipeptides (CODPs) with strong anthelmintic properties; acts as an ionophore.
 
CS-3376 MK-3697 September 2014
MK-3697 is an isonicotinamide small molecule, acting as a potent and selective Orexin 2 receptor antagonist with Ki = 0.
 
CS-3375 PF-573228 September 2014
PF-573228 is a potent and selective FAK inhibitor with IC50 of 4 nM for inhibiton of purified recombinant catalytic fragment of FAK; inhibits FAK phosphorylation on Tyr(397) with an IC(50) of 30-100 nM.
 
CS-3374 JZL195 September 2014
JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor with IC50 of 13 nM and 19 nM for mouse brain FAAH and MAGL respectively.
 
CS-3373 JZL-184 September 2014
JZL 184 is a potent and selective inhibitor of MAGL with IC50 of 8 nM and 4 μM for inhibition of MAGL and FAAH in mouse brain membranes respectively.
 
CS-3372 Pifithrin-beta September 2014
Pifithrin-β (Cyclic Pifithrin-α) is a potent p53 inhibitor with IC50 of 23 uM in an antiproliferative assay in the human ovarian carcinoma cell line, IGROV-1.
 
CS-3371 Pifithrin-beta-hydrobromide September 2014
Pifithrin-β HBr (Cyclic Pifithrin-α HBr) is a potent p53 inhibitor with IC50 of 23 uM in an antiproliferative assay in the human ovarian carcinoma cell line, IGROV-1.
 
CS-3370 5852-78-8 September 2014
IOX1 is the most potent broad-spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases; IC50 for KDM4A/KDM3A is 0.
 
CS-3369 Kartogenin September 2014
Kartogenin(KGN) is a small molecule stimulator of chondrogenesis; promotes chondrocyte differentiation(EC50=100 nM) and binds to filamin A.
 
CS-3368 D8-MMAE September 2014
D8-MMAE(D8-Monomethyl auristatin E; D8-Vedotin) is a deuterated form of MMAE.
 
CS-3367 GS-7340-fumarate September 2014
GS-7340(Tenofovir alafenamide) is a prodrug of tenofovir (TFV) that more efficiently delivers TFV into lymphoid cells and tissues than TFV disoproxil fumarate.
 
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CS-0757 SB-705498
SB-705498 is a potent, selective and orally bioavailable transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with a pIC50 of 7.
CS-0766 Aripiprazole
Aripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.
CS-0765 CYT387 sulfate salt
CYT387 sulfate(momelotinib) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3.
CS-0645 Rimonabant
Rimonabant(SR141716) is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.
CS-0494 XAV-939
XAV939 is a small molecule and selective Wnt pathway transcription factor β-catenin-mediated transcription inhibitor and axin stabilizing agent with IC50 of 11 and 4 nM for the inhibition of TNKS1 and TNKS2, respectively.
CS-0264 DAPT
DAPT(GSI-IX) is an inhibitor of γ-secretase; DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, cerebrospinal fluid and plasma in vivo.
CS-0361 Boceprevir
Boceprevir(EBP-520, SCH503034) is an HCV protease inhibitor (Ki=14 nM) for the treatment of hepatitis C virus infection.
CS-0592 YM-201636
YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α.
CS-0613 Tideglusib
Tideglusib(NP-031112) is an irreversible, non ATP-competitive GSK-3β inhibitor with IC50 of 60 nM.
CS-0625 Avosentan
Avosentan(Ro 67-0565; SPP-301) is a potent, selective endothelin receptor(ETA receptor) antagonist.
CS-0609 SCH 527123
SCH-527123 is a potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively.
CS-0612 T 705
T 705(Favipiravir) is a RNA-directed RNA polymerase NS5B inhibitor.
CS-0614 Suvorexant
Suvorexant (MK-4305) is a potent dual OX receptor antagonist with Ki of 0.
CS-0627 MEK162
MEK162(ARRY-438162; ARRY-162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM.
CS-0608 BMS-754807
BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.

 
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