You can visit our distribution website in Japan at  フナコシ株式会社 www.funakoshi.co.jp    電話番号:81-3-5684-1620   FAX番号:81-3-5684-1775
Tel: 732-484-9848
Fax: 888-484-5008
Email: sales@chemscene.com
   
Buliding blocks
Intermediates
Bioactive molecules
Product Pathways
All Targets
Anti-infection
Antibody-drug conjugate....
Apoptosis
Biochemical Reagent
Cell Cycle/DNA Damage
GPCR/G protein
Immunology/Inflammation
JAK/STAT Signaling
MAPK/ERK Pathway
Membrane Transporter/Io....
Metabolism/Protease
Neuronal Signaling
NF-KB
Others
PI3K/Akt/mTOR
Protein Tyrosine Kinase....
TGF-beta/Smad
Vitamin D Related
Wnt/Hedgehog/Notch
Research Area
Cancer
Cardiovascular Disease
Endocrinology
Infection
Metabolic Disease
Neurological Disease
Others
Inflammation/Immunology
Product Type
All Products
New Products
Featured Products
Welcome to ChemScene Chemicals
New Products
Cat.No. Product Name / Introduction Added
CS-3420 ESI-09 October 2014
ESI-09 is a novel noncyclic nucleotide EPAC antagonist that is capable of specifically blocking intracellular EPAC-mediated Rap1 activation and Akt phosphorylation, as well as EPAC-mediated insulin secretion in pancreatic β cells with IC50 of 1.
 
CS-3419 Firocoxib October 2014
Firocoxib(ML 1785713) is a potent and selective cyclooxygenase (COX)-2 inhibitor with IC50 of 0.
 
CS-3418 Brivaracetam October 2014
Brivaracetam(UCB-34714) is a 4-substituted pyrrolidone butanamide as agent with significant antiepileptic activity; high affinity SV2A ligand and also shows an ability to inhibit Na+ channels.
 
CS-3417 AC-55541 October 2014
AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.
 
CS-3416 AC710-Mesylate October 2014
AC710 Mesylate is a potent, selective PDGFR-family kinases inhibitor with Kd values of 0.
 
CS-3415 AC710 October 2014
AC710 is a potent, selective PDGFR-family kinases inhibitor with Kd values of 0.
 
CS-3414 CGP-42112 October 2014
CGP-42112(CGP-42112A) is a potent Angiotensin-II subtype 2 receptor(AT2 R) agonist.
 
CS-3413 Angiotensin-1-7 October 2014
Angiotensin (1-7) is a endogenous peptide fragment which can induces vasorelaxation through release of NO and prostaglandins, perhaps through activation of a non-AT1, non-AT2 receptor, Mas.
 
CS-3412 Mps1-IN-3 October 2014
Mps1-IN-3 is a selective and highly potent MPS1 kinase inhibitor with an IC50 of 50 nM.
 
CS-3411 Defactinib-hydrochloride October 2014
 
CS-3410 Defactinib October 2014
Defactinib(VS-6063; PF-04554878) is a potent FAK phosphorylation inhibitor; overcomes YB-1–mediated paclitaxel resistance by an AKT-dependent pathway.
 
CS-3408 MMAD-hydrochloride October 2014
Monomethyl auristatin D Hcl (MMAD Hcl), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
 
CS-3407 10-Deacetyl-7-xylosyl-paclitaxel October 2014
10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility.
 
CS-3405 AZD-9291-dimesylate October 2014
AZD-9291 dimesylate is a potent and selective mutated forms EGFR inhibitor(Exon 19 deletion EGFR IC50=12.
 
CS-3409 LCZ696 October 2014
LCZ696 is a first-in-class dual inhibitor of the angiotensin II receptor(AT II receptor) and neprilysin; a novel single molecule comprising molecular moieties of valsartan and NEP inhibitor prodrug AHU377 (1:1 ratio).
 
Previous Page  Next Page  1/167Page

Find Multiple Products by
Catalog Number
Continue
 
Recommended Products
CS-0757 SB-705498
SB-705498 is a potent, selective and orally bioavailable transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with a pIC50 of 7.
CS-0766 Aripiprazole
Aripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.
CS-0765 CYT387 sulfate salt
CYT387 sulfate(momelotinib) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3.
CS-0645 Rimonabant
Rimonabant(SR141716) is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.
CS-0494 XAV-939
XAV939 is a small molecule and selective Wnt pathway transcription factor β-catenin-mediated transcription inhibitor and axin stabilizing agent with IC50 of 11 and 4 nM for the inhibition of TNKS1 and TNKS2, respectively.
CS-0264 DAPT
DAPT(GSI-IX) is an inhibitor of γ-secretase; DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, cerebrospinal fluid and plasma in vivo.
CS-0361 Boceprevir
Boceprevir(EBP-520, SCH503034) is an HCV protease inhibitor (Ki=14 nM) for the treatment of hepatitis C virus infection.
CS-0592 YM-201636
YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α.
CS-0613 Tideglusib
Tideglusib(NP-031112) is an irreversible, non ATP-competitive GSK-3β inhibitor with IC50 of 60 nM.
CS-0625 Avosentan
Avosentan(Ro 67-0565; SPP-301) is a potent, selective endothelin receptor(ETA receptor) antagonist.
CS-0609 SCH 527123
SCH-527123 is a potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively.
CS-0612 T 705
T 705 (Favipiravir) is an experimental anti-viral drug with activity against many RNA viruses; RNA-directed RNA polymerase NS5B inhibitor.
CS-0614 Suvorexant
Suvorexant (MK-4305) is a potent dual OX receptor antagonist with Ki of 0.
CS-0627 MEK162
MEK162(ARRY-438162; ARRY-162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM.
CS-0608 BMS-754807
BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.

 
Latest Catalog
Please send email to info@chemscene.com for our latest catalog.

 

CHEMSCENE, LLC
Tel: 732-484-9848
Fax: 888-484-5008
Email: sales@chemscene.com
Address: 11 Deer Park Drive, Suite 102D Monmouth Junction, NJ 08852.
Products are for research use only. Not for human use. We do not sell to patients. Sitemap | Inhibitor © Copyright 2012. All Rights Reserved.