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New Products
Cat.No. Product Name / Introduction Added
CS-5644 Moxisylyte-hydrochloride June 2016
Moxisylyte (hydrochloride) is (alpha 1-blocker) antagonist,it can vasodilates cerebral vessels without reducing blood pressure。It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents.
 
CS-5638 GDC-0084 June 2016
GDC-0084 is a potent, selective inhibitor of Class I PI3K and mTOR with good penetration across the blood-brain barrier.
 
CS-5642 RS-1 June 2016
RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51.
 
CS-5640 Ciraparantag June 2016
Ciraparantag is a thrombin and factor Xa inhibitors as well as to heparin-based anticoagulants through non-covalent hydrogen bonding and charge interactions.
 
CS-5643 EPZ015866 June 2016
EPZ015866 (GSK591) is a potent selective inhibitor of the arginine methyltransferase PRMT5.
 
CS-M0862 Bergaptol June 2016
Bergaptol A hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.
 
CS-5627 Methyl-linolenate June 2016
Methyl linolenate is a polyunsaturated fattly acid (PUFA).
 
CS-5639 SCH-58261 June 2016
SCH 58261 is the adenosine A2A receptor competitive antagonist.
 
CS-5641 EL-102 June 2016
EL102 is a inhibitor of HIF1α , Which can inhibit tubulin polymerisation and decreased microtubule stability.
 
CS-5637 ONO-4059-hydrochloride June 2016
ONO-4059 is a selective and novel inhibitor of BTK with IC50 2.
 
CS-5636 JI-101 June 2016
JI-101 is an oral multi-kinase inhibitor that targets vascular endothelial growth factor receptor type 2 (VEGFR-2), platelet derived growth factor receptor β (PDGFR-β), and ephrin type-B receptor 4 (EphB4).
 
CS-5634 Celgosivir June 2016
Celgosivir is a novel α-glucosidase I inhibitor, an enzyme that plays a critical role in viral maturation by initiating the processing of the N-linked oligosaccharides of viral envelope glycoproteins.
 
CS-5633 Castanospermine June 2016
Castanospermine inhibits all forms of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids).
 
CS-5628 ML264 June 2016
ML 264 is a potent Krüppel-like factor 5 (KLF5) inhibitor.
 
CS-5635 BTZ043 June 2016
BTZ043 is a inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), It can display nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro.
 
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Recommended Products
CS-0757 SB-705498
SB-705498 is a potent, selective and orally bioavailable transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with a pIC50 of 7.
CS-0766 Aripiprazole
Aripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.
CS-0765 CYT387 sulfate salt
CYT387 sulfate(momelotinib) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3.
CS-0645 Rimonabant
Rimonabant(SR141716) is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.
CS-0494 XAV-939
XAV939 is a small molecule and selective Wnt pathway β-catenin-mediated transcription inhibitor and axin stabilizing agent with IC50 of 11 and 4 nM for the inhibition of TNKS1 and TNKS2, respectively.
CS-0264 DAPT
DAPT(GSI-IX) is an inhibitor of γ-secretase; DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, cerebrospinal fluid and plasma in vivo.
CS-0361 Boceprevir
Boceprevir(EBP-520, SCH503034) is an HCV protease inhibitor (Ki=14 nM) for the treatment of hepatitis C virus infection.
CS-0592 YM-201636
YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α.
CS-0613 Tideglusib
Tideglusib(NP-031112) is an irreversible, non ATP-competitive GSK-3β inhibitor with IC50 of 60 nM.
CS-0625 Avosentan
Avosentan(Ro 67-0565; SPP-301) is a potent, selective endothelin receptor(ETA receptor) antagonist.
CS-0609 SCH 527123
SCH-527123 is a potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively.
CS-0627 MEK162
MEK162(ARRY-438162; ARRY-162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM.
CS-0608 BMS-754807
BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.

 
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