(+)-JQ1 PA
CAS No. : 2115701-93-2

(+)-JQ1 PA
Cat. No. : CS-0064464
M. Wt. : 437.95
Size Stock Price Quantity Add to Cart Quotation Online
5mg In-stock USD 140.0
10mg In-stock USD 220.0
25mg In-stock USD 420.0
50mg In-stock USD 710.0
100mg In-stock USD 1300.0
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  • Data Sheet

  • Introduction

  • SDS

  • COA & Spectra

Name: (+)-JQ1 PA; 
Cat. No. : CS-0064464
CAS No. : 2115701-93-2
Formula: C22H20ClN5OS
M. Wt. : 437.95
Solubility: 10 mM in DMSO


(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1, with an IC50 of 10.4 nM. IC50 & Target: 10.4 nM (BET)[1]. In Vitro: (+)-JQ1 PA is a derivative of JQ1, which is the inhibitor of BET. The IC50 of (+)-JQ1 PA for BET is 10.4 nM, and the IC50 of JQ1 is 14.3 nM in MV4;11 cells[1].


Cell Assay: [1]Proliferation of MV4;11 cells after 72 hours of treatment, comparing JQ1 versus JQ1-PA are tested. Cell cycle profile of MV4;11 cells after 48 hours of treatment with DMSO, JQ1, JQ1-PA, or JQ1-TCO (all compounds used at 500 nM) are tested[1].


Tyler DS, et al. Click chemistry enables preclinical evaluation of targeted epigenetic therapies. Science. 2017 Jun 30;356(6345):1397-1401.

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