Biochemistry
Biochemistry is a discipline that studies chemical processes and metabolism in organisms, focusing on the structure, function, interaction, metabolism and regulation of biological macromolecules (such as proteins, nucleic acids, lipids, carbohydrates, etc.) in cells. It is an interdisciplinary subject that combines knowledge from multiple fields such as chemistry, biology, physics and medicine, and is the basis for understanding life phenomena.
Biochemistry
Biochemistry is a discipline that studies chemical processes and metabolism in organisms, focusing on the structure, function, interaction, metabolism and regulation of biological macromolecules (such as proteins, nucleic acids, lipids, carbohydrates, etc.) in cells. It is an interdisciplinary subject that combines knowledge from multiple fields such as chemistry, biology, physics and medicine, and is the basis for understanding life phenomena.
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Albumin Binding Agents
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Alkaloids
Alkaloids are a class of nitrogen-containing alkaline organic compounds that exist in nature. They have alkali-like properties, so they were also called pseudo-alkalis in the past. Most of them have complex ring structures, with nitrogen mostly contained in the ring . They have significant biological activity and are one of the important active ingredients in Chinese herbal medicines. They are optically active.
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Amino Acids
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Antibody-Drug Conjugates (ADC) Preparation Research Reagents
ADC drugs are targeted drugs formed by coupling monoclonal antibodies with small molecule toxin drugs through linkers. ADC consists of three parts: antibodies, small molecule toxins and linkers. Each component needs to have corresponding characteristics. The antibody needs to have high specificity and low immunogenicity; the linker needs to be stable in the circulatory system and can effectively release cytotoxins in the tumor environment, and the small molecule toxin needs to be stable under physiological conditions and have strong lethality to tumor cells; the ideal ADC drug needs to remain stable in the blood circulation, accurately reach the treatment target, and ultimately release cytotoxicity near the target.
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Bioactive Compounds (Other)
Bioactive compounds are natural compounds found in various foods and plants that have antioxidant, anti-inflammatory, anti-cancer and other medicinal properties in the human body.
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Bioconjugation
Bioconjugation is the process of connecting two molecules (at least one of which is a biomacromolecule) through a chemical covalent bond, including the coupling of lysine and cysteine and photochemically induced free radical reactions. It is widely used in the research of proteins, DNA, RNA and carbohydrates, such as ligand discovery, disease diagnosis and efficient screening.
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Biological Buffers
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Chemical Chaperones
Chemical chaperones are small molecules that help proteins maintain their correct conformation and function in cells under stressful conditions, helping proteins fold, stabilize and prevent aggregation, providing protection against cellular stress and promoting normal protein functioning.
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Lipids
Lipids are a class of organic molecules that include fats, oils, and phospholipids. Characterized by their hydrophobic nature, they are important building blocks of cell membranes, energy storage, and insulation in living organisms. Lipids play a vital role in a variety of physiological processes, such as hormone production, vitamin absorption, and cell signaling.
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Luminescent Compounds/Detection
Luminescent compounds are chemical substances that are able to emit light in response to stimuli such as ultraviolet light or electric fields. These compounds are often used in detection applications, where their ability to emit light can be used to track the presence of specific molecules or ions in a sample. Detection methods using luminescent compounds are often used in fields such as analytical chemistry, biochemistry, and materials science to study the properties and interactions of various substances.
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Nucleosides, Nucleotides, Oligonucleotides
Nucleoside: composed of sugar and base, it is one of the building blocks of nucleic acid and also participates in energy transport and signal transduction. Nucleotide: composed of nucleoside and phosphate, it is the basic unit of DNA and RNA and has important energy and signal transduction functions. Oligonucleotide: short-chain nucleic acid, commonly used in molecular biology techniques such as gene research, gene editing, and gene silencing.
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Peptides
Peptides are a class of compounds between amino acids and proteins formed by dehydration condensation of α-amino acids. Many active substances in the human body exist in the form of peptides, which are biologically active substances involved in various cell functions in the body.
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Pharmaceutical Research Reagents
Active pharmaceutical ingredients are core components in the drug development and production process. They are substances that have therapeutic effects or the ability to prevent or diagnose diseases.
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Phenylpropanoids, Aromatic Polyketides
Phenylpropanoid compounds are widely found in plants and have become important raw materials in many fields such as medicine, food, and cosmetics. They have broad application prospects in the fields of medicine and biology. Common ones include coumarins and lignans. Aromatic polyketides are a class of compounds produced by bacteria, fungi, and plants through polyketide synthases.
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Porphyrins
Porphyrins are a class of macromolecular heterocyclic compounds composed of four pyrrole subunits with α-carbon atoms interconnected by methine bridges (=CH-). Porphyrins play an important role in various biochemical processes and can be used as research and diagnostic reagents. Their study is crucial to understanding the operation of biological systems at the molecular level.
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Proteins and Derivatives
Protein is an important component of all cells and tissues in the human body. Protein can be modified or broken down into smaller molecules, called protein derivatives, through processes such as hydrolysis or denaturation. These molecules play a vital role in structural support, enzyme catalysis , signal transduction, and immune response regulation.
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Stabilization of Biomolecules
Biomolecule stabilization refers to maintaining the structural integrity and biological activity of these molecules under various environmental conditions to prevent degradation or denaturation of biomolecules such as proteins, enzymes, and nucleic acids.
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Steroids
Steroids, also known as steroidal compounds, are a general term for a large class of cyclopentyl perhydrophenanthrene derivatives that are widely distributed in the biological world. They play an important role in various biological processes, such as regulating metabolism, inflammation, immune response and growth .
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Terpenes
Terpenes are a class of naturally occurring hydrocarbons that are widely found in plants and can be obtained from many plants, especially conifers. It is the general name for a series of terpenoid compounds, which are olefin compounds with a molecular formula that is an integer multiple of isoprene. Many terpenoid compounds have important physiological activities and are an important source for studying natural products and developing new drugs.
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Vitamins and Related Compounds
Vitamins and related compounds are organic substances that are necessary for various biochemical processes in the human body. They play a vital role in maintaining overall health and preventing diseases related to deficiency. These compounds are divided into different categories, such as fat-soluble vitamins ( A, D, E, and K) and water-soluble vitamins (B vitamins and vitamin C).
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Antibody-Drug Conjugates (ADC) Preparation Research Reagents
ADC drugs are targeted drugs formed by coupling monoclonal antibodies with small molecule toxin drugs through linkers. ADC consists of three parts: antibodies, small molecule toxins and linkers. Each component needs to have corresponding characteristics. The antibody needs to have high specificity and low immunogenicity; the linker needs to be stable in the circulatory system and can effectively release cytotoxins in the tumor environment, and the small molecule toxin needs to be stable under physiological conditions and have strong lethality to tumor cells; the ideal ADC drug needs to remain stable in the blood circulation, accurately reach the treatment target, and ultimately release cytotoxicity near the target.
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Drug Delivery Systems (DDS)
Drug delivery system refers to a technical system that comprehensively regulates the distribution of drugs in the body in terms of space, time and dosage. It improves the health of patients by enhancing the delivery of therapeutic drugs to their target sites and minimizing accumulation outside the target. Compared with traditional drug delivery systems based on conventional oral tablets, capsules, intravenous injections, inhalation preparations and transdermal patches, new drug delivery systems refer to systems that use new drug delivery technologies with overall high technical barriers (such as drug delivery technologies based on liposomes, nanoparticles, microspheres, exosomes, engineered AAV vectors, 3D printed drug preparations, etc.) to deliver various types of drugs. New drug delivery systems can improve the efficacy of drugs and reduce toxic side effects by adjusting the delivery and release sites of drugs, changing the metabolic behavior of drugs in the body, improving the sustained-release and controlled-release properties of drugs, and the properties of penetrating physiological barriers (such as the blood-brain barrier).
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Pharmaceutical Research Reagents
Active pharmaceutical ingredients are core components in the drug development and production process. They are substances that have therapeutic effects or the ability to prevent or diagnose diseases.
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Proteolysis Targeting Chimera Research Reagents
PROTACs consist of a small molecule ligand that binds to a target protein and brings it into proximity with an E3 ubiquitin ligase, resulting in its ubiquitination and subsequent degradation by the proteasome machinery. These research reagents are used to study protein function, discover new drug targets , and develop novel therapeutic strategies for diseases such as cancer and neurodegenerative disorders.
Pharmaceutical Research Reagents
- Antimicrobial Ingredients
- Antiparasitic Ingredients, Antiprotozoal Ingredients, Antihelminthic Ingredients
- Antiviral Research Reagents
- Antitumor Research Reagents
- Antihypertensive Ingredients
- Antilipemic Ingredients
- Antithrombotic Ingredients
- Antidiabetic Ingredients
- Neurotransmitter Agent Ingredients
- Anti-inflammatory Ingredients
- Anti-allergic Ingredients
- Immunosuppressant Ingredients
- Anti-rheumatoid Arthritis Ingredients
- Anti-osteoporosis Ingredients
- Pharmaceutical Research Reagents (Others)
- Cosmetic Research Reagents
- Antifungal Ingredients
- Contrast Medium Ingredients
- Anti-Constipation Ingredients
Bioconjugation
- Enzyme Cleavable Linkers (Cleave Motif)
- Biotins, Streptavidins
- Functionality Creating Reagents
- Functional Group Blocking Reagents
- Heterobifunctional Cross-Linkers
- PEGylation Reagents and PEG Spacers
- Zero-length Crosslinkers
- Albumin Binding Modification Reagents
- Homobifunctional Cross-Linkers
- Copper-free Click Reaction Reagents
- Photo-reactive Crosslinkers
- N-Terminal Cysteine Residue-specific Conjugation Reagents
Pharmaceutical Research Reagents
- Antimicrobial Ingredients
- Antiparasitic Ingredients, Antiprotozoal Ingredients, Antihelminthic Ingredients
- Antiviral Research Reagents
- Antitumor Research Reagents
- Antihypertensive Ingredients
- Antilipemic Ingredients
- Antithrombotic Ingredients
- Antidiabetic Ingredients
- Neurotransmitter Agent Ingredients
- Anti-inflammatory Ingredients
- Anti-allergic Ingredients
- Immunosuppressant Ingredients
- Anti-rheumatoid Arthritis Ingredients
- Anti-osteoporosis Ingredients
- Pharmaceutical Research Reagents (Others)
- Cosmetic Research Reagents
- Antifungal Ingredients
- Contrast Medium Ingredients
- Anti-Constipation Ingredients
Drug Delivery Systems (DDS)
- Prodrug Ingredients
- Natural Polymers (for DDS)
- Monomers for Synthetic Polymers (for DDS)
- Polyethyleneglycols (PEG) (for DDS)
- PEGylation Reagents (for DDS)
- Cyclodextrins (for DDS)
- Drug Delivery Systems (DDS) Research Reagents (Others)
- Phospholipids (for DDS)
- Lipids (Other) (for DDS)
- Synthetic Polymers (for DDS)
- Chelating Agents (for DDS)