KIF18A is a kinesin motor protein that plays a critical role in the regulation of mitosis, specifically in the control of chromosome alignment during cell division. It functions by transporting microtubules to the mitotic spindle, ensuring accurate chromosome segregation. Overexpression or dysregulation of KIF18A has been implicated in various cancers, as it can contribute to chromosomal instability and tumor progression. Due to its pivotal role in cell division, KIF18A has emerged as a potential therapeutic target for cancer treatment, with inhibitors being explored for their ability to disrupt tumor cell proliferation.