C-H Activation

C-H bond activation plays an important role in the chemical and industrial fields. Common C-H bond activation methods: 1. Transition metal catalyzed CH bond activation reaction: For example, transition metal catalysts such as palladium (Pd), platinum (Pt), and ruthenium (Ru) can reduce the fracture energy of the CH bond by forming a transition state complex, thereby promoting the activation of the CH bond. 2. Oxidation method: For example, using an oxidant (such as hydrogen peroxide, peroxide) at high temperature or under the action of a catalyst to activate the CH bond and generate an oxidation product. 3. Photocatalysis and electrocatalysis: Some photocatalysts (such as TiO₂) and electrocatalysts can use light energy or electrical energy to activate the CH bond for environmentally friendly organic synthesis. 4. Free radical reaction: Free radical reaction is another common CH bond activation pathway, which is often used in the chlorination, bromination or oxidation reactions of hydrocarbon compounds.