Chemical Biology
Chemical biology is the science that studies the chemical basis of life processes. It provides an important theoretical basis for new drug discovery by using chemical theories and methods to study life phenomena and processes and by exploring the pathways and mechanisms of intervention and adjustment of the occurrence and development of diseases.
Chemical Biology
Chemical biology is the science that studies the chemical basis of life processes. It provides an important theoretical basis for new drug discovery by using chemical theories and methods to study life phenomena and processes and by exploring the pathways and mechanisms of intervention and adjustment of the occurrence and development of diseases.
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Monosaccharides
Monosaccharides refer to molecules that cannot be simply hydrolyzed into smaller sugars. According to the position of the carbonyl group, they are divided into two categories: aldose and ketose. According to the number of carbon atoms in the monosaccharide, it can also be divided into triose, tetrose, pentose, hexose, and heptose. The most abundant monosaccharides in nature are pentoses and hexoses. Such as glyceraldehyde, a three-carbon sugar; erythrose and thulose, four-carbon sugars; arabinose, ribose, xylose, and lyxose, five-carbon sugars; glucose, mannose, fructose, and galactose, six-carbon sugars. Monosaccharides in food are mainly hexoses (six-carbon sugars).
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Functional Oligosaccharides
Functional oligosaccharides refer to short-chain sugar molecules with specific biological activities or functions, usually composed of 2 to 1 monosaccharide units. They play a variety of important roles in organisms and are widely used in food, nutrition, health care, medicine and other fields. Functional oligosaccharides play an important role in multiple biological processes. They not only have health benefits such as prebiotics, immunomodulation, anti-inflammatory and antioxidant, but also provide a variety of potential applications in medicine, nutrition, food industry and other fields.
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Oligosaccharides by Component Sugar
Oligosaccharide composition refers to a method of studying the chemical structure and biological function of oligosaccharides by analyzing and disassembling the individual monosaccharide (simple sugar) components contained in oligosaccharide molecules. Oligosaccharides are usually composed of 2 to 1 monosaccharide units connected by glycosidic bonds. They play important roles in organisms, such as cell recognition, immune response, signal transduction, etc.
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Glyco Building Blocks
Sugar building blocks refer to the basic monosaccharide units and their derivatives that make up sugar chains. The structure of a sugar chain is usually composed of different monosaccharide molecules connected by glycosidic bonds, and these monosaccharide molecules are called glycosyl building blocks. They are the basis for synthesizing complex sugar chains, studying glycobiology, and developing sugar-related drugs.
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Applications Using Glyco-materials
Glycomaterials are a class of materials containing sugar molecules or sugar structures, which are widely used in many fields such as biomedicine, chemical engineering, and environmental protection. Glycomaterials usually have strong biocompatibility, tunability, and hydrophilicity, and therefore play an important role in many applications.
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Oligosaccharides
Oligosaccharides, also known as oligosaccharides or less sugars, are a type of carbohydrate composed of 2 to 1 monosaccharide molecules connected by glycosidic bonds. Oligosaccharides usually connect 2-4 monosaccharides through glycosidic bonds to form small polymers, including functional oligosaccharides and ordinary oligosaccharides. The common characteristics of this type of oligosaccharides are that they are difficult to be digested and absorbed by the gastrointestinal tract, have low sweetness, low calories, and basically do not increase blood sugar and blood lipids. Oligosaccharides are widely used in food, health products, beverages, medicine, feed additives and other fields.
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Disaccharides
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Polysaccharides
Polysaccharide is a polymeric carbohydrate formed by multiple monosaccharide molecules linked by glycosidic bonds, and is composed of at least one monosaccharide. Polysaccharide is not a pure chemical substance, but a mixture of substances with different polymerization degrees. It is usually insoluble in water, has no sweet taste, cannot form crystals, and has no reducing and mutarotation phenomena. Polysaccharides have significant biological activities in anti-tumor, anti-inflammatory, anti-viral, hypoglycemic, anti-aging, anti-coagulation and immune promotion.
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Reagents for Oligosaccharide Synthesis
Reagents for Oligosaccharide Synthesis are chemicals or catalysts used to synthesize oligosaccharides (such as disaccharides, trisaccharides, tetrasaccharides, etc.). These reagents often play a key role in organic synthesis and biochemical research, facilitating the connection of monosaccharides to form more complex carbohydrate structures.
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Sugars (Other)
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Tetrasaccharides
Tetrasaccharides are oligosaccharides formed by four monosaccharide molecules connected by condensation reaction (dehydration reaction). Like other types of oligosaccharides, tetrasaccharides have important biological functions and applications in nature.
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Trisaccharides
Trisaccharides are carbohydrates composed of three monosaccharide molecules connected by glycosidic bonds. They are not as common in nature as disaccharides and monosaccharides, but still play an important role in the metabolism, nutrient absorption and cell function of some organisms. Common trisaccharides include maltotriose. The functions of trisaccharides in the human body include providing energy, promoting intestinal health, regulating blood sugar, supporting the immune system, etc. They are not only an important source of energy for the human body, but also indirectly promote overall health through their effects on intestinal flora.
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Enzyme, Lectin, Antibody
Enzymes, lectins and antibodies are three important protein molecules in organisms, each with different biological functions and widely involved in physiological and immune processes. These molecules play a vital role in maintaining the normal function of the body and defending against foreign invasions.
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Conjugation Chemistry/Click Chemistry
Click chemistry is a synthetic concept introduced by chemist K. Barry Sharpless in 21 years. Its main purpose is to quickly and reliably complete the chemical synthesis of various molecules by splicing small units. It particularly emphasizes the development of new combinatorial chemistry methods based on carbon-heteroatom bond (CXC) synthesis, and uses these reactions (click reactions) to simply and efficiently obtain molecular diversity.
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Bioconjugation
Bioconjugation is the process of connecting two molecules (at least one of which is a biomacromolecule) through a chemical covalent bond, including the coupling of lysine and cysteine and photochemically induced free radical reactions. It is widely used in the research of proteins, DNA, RNA and carbohydrates, such as ligand discovery, disease diagnosis and efficient screening.
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Nucleic Acid Chemistry
Nucleic acid chemistry covers a series of processes such as the synthesis, modification, mutation, and degradation of DNA and RNA. These chemical reactions are the basis of information transmission and expression regulation in life. With the development of molecular biology technology, nucleic acid chemistry has become increasingly important in diseases. Its applications in the fields of therapy, genetic engineering, molecular diagnosis, etc. are becoming increasingly extensive, showing important scientific and clinical value.
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Peptide Chemistry
Peptides are widely present in nature and in living organisms. They are a type of natural substance composed of two or more amino acids connected by peptide bonds. They are also the product of incomplete hydrolysis of proteins. So far, a wide variety of peptides have been found in organisms, and they play an important role in participating in and regulating life activities in the body. According to the number of amino acids, they can be divided into oligopeptides (2-1 amino acids) and polypeptides (1-1 amino acids).
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PEGylation
Polyethylene glycol (PEG), also known as polyethylene oxide (PEO) or polyoxyethylene (POE), refers to oligomers or polymers of ethylene oxide. Polyethylene glycol has excellent lubricity, moisturizing and dispersibility, and can be used as a softener and antistatic agent. It is widely used in cosmetics, pharmaceuticals, chemical fibers, rubber, plastics, papermaking, paints, electroplating, pesticides, metal processing and food processing industries.
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Linkers and Crosslinkers
Cross-linkers are molecules with two or more reactive ends that can be chemically linked to specific functional groups (primary amines, sulfhydryls, etc.) on proteins or other molecules. This technique, often referred to as bioconjugation when used with proteins and other biomolecules, is an important component of many proteomics methods, including the creation of detectable probes for western blotting and ELISA, as well as strategies to study protein structure and interactions.
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Drug Delivery Systems (DDS)
Drug delivery system refers to a technical system that comprehensively regulates the distribution of drugs in the body in terms of space, time and dosage. It improves the health of patients by enhancing the delivery of therapeutic drugs to their target sites and minimizing accumulation outside the target. Compared with traditional drug delivery systems based on conventional oral tablets, capsules, intravenous injections, inhalation preparations and transdermal patches, new drug delivery systems refer to systems that use new drug delivery technologies with overall high technical barriers (such as drug delivery technologies based on liposomes, nanoparticles, microspheres, exosomes, engineered AAV vectors, 3D printed drug preparations, etc.) to deliver various types of drugs. New drug delivery systems can improve the efficacy of drugs and reduce toxic side effects by adjusting the delivery and release sites of drugs, changing the metabolic behavior of drugs in the body, improving the sustained-release and controlled-release properties of drugs, and the properties of penetrating physiological barriers (such as the blood-brain barrier).
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Nucleic Acid Chemistry
Nucleic acid chemistry covers a series of processes such as the synthesis, modification, mutation, and degradation of DNA and RNA. These chemical reactions are the basis of information transmission and expression regulation in life. With the development of molecular biology technology, nucleic acid chemistry has become increasingly important in diseases. Its applications in the fields of therapy, genetic engineering, molecular diagnosis, etc. are becoming increasingly extensive, showing important scientific and clinical value.
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Peptide Chemistry
Peptides are widely present in nature and in living organisms. They are a type of natural substance composed of two or more amino acids connected by peptide bonds. They are also the product of incomplete hydrolysis of proteins. So far, a wide variety of peptides have been found in organisms, and they play an important role in participating in and regulating life activities in the body. According to the number of amino acids, they can be divided into oligopeptides (2-1 amino acids) and polypeptides (1-1 amino acids).
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PEGylation
Polyethylene glycol (PEG), also known as polyethylene oxide (PEO) or polyoxyethylene (POE), refers to oligomers or polymers of ethylene oxide. Polyethylene glycol has excellent lubricity, moisturizing and dispersibility, and can be used as a softener and antistatic agent. It is widely used in cosmetics, pharmaceuticals, chemical fibers, rubber, plastics, papermaking, paints, electroplating, pesticides, metal processing and food processing industries.
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Linkers and Crosslinkers
Cross-linkers are molecules with two or more reactive ends that can be chemically linked to specific functional groups (primary amines, sulfhydryls, etc.) on proteins or other molecules. This technique, often referred to as bioconjugation when used with proteins and other biomolecules, is an important component of many proteomics methods, including the creation of detectable probes for western blotting and ELISA, as well as strategies to study protein structure and interactions.
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Specialized Building Blocks for Drug Discovery
Specialized Building Blocks for Drug Discovery refer to tools and frameworks designed and optimized specifically for the drug discovery process.
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Albumin Binding Agents
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Antibody-Drug Conjugates (ADC) Preparation Research Reagents
ADC drugs are targeted drugs formed by coupling monoclonal antibodies with small molecule toxin drugs through linkers. ADC consists of three parts: antibodies, small molecule toxins and linkers. Each component needs to have corresponding characteristics. The antibody needs to have high specificity and low immunogenicity; the linker needs to be stable in the circulatory system and can effectively release cytotoxins in the tumor environment, and the small molecule toxin needs to be stable under physiological conditions and have strong lethality to tumor cells; the ideal ADC drug needs to remain stable in the blood circulation, accurately reach the treatment target, and ultimately release cytotoxicity near the target.
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Building Blocks for Pharmaceutical Ingredients
Drug building blocks are a class of basic units used to synthesize complex compounds with specific activities. They usually have active functional groups and can be used for the "bottom-up" assembly of characteristic molecular structures. In the process of new drug research and development, drug building blocks are widely used in key links such as drug target discovery, screening and optimization of lead compounds and lead compounds, and determination of clinical candidates.
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Proteolysis Targeting Chimera Research Reagents
PROTACs consist of a small molecule ligand that binds to a target protein and brings it into proximity with an E3 ubiquitin ligase, resulting in its ubiquitination and subsequent degradation by the proteasome machinery. These research reagents are used to study protein function, discover new drug targets , and develop novel therapeutic strategies for diseases such as cancer and neurodegenerative disorders.
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Aldehyde Reactive Fluorophores and Labels
Aldehyde-reactive fluorescent dyes form stable complexes by covalently binding to amino, hydroxyl and other functional groups in biomolecules. This reaction usually involves the formation of imine or ether bonds to achieve labeling. These fluorescent markers have a wide range of applications in biomedical research, cell imaging, protein labeling and other chemical analysis.
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Amino Acid Azides/Alkynes
Amino acid azides are a class of compounds that introduce an azide group (-N₃) into amino acid molecules. Amino acid alkynes are amino acids containing an alkyne group. The alkyne-azide group is a highly active functional group that can participate in a variety of chemical reactions, especially click chemistry reactions such as CuAAC (copper-catalyzed azide-alkyne cycloaddition) reactions. They are widely used in bioimaging, molecular labeling, and bioconjugation fields.
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Azides
Azide click chemistry is a chemical process that forms a stable triazole bond by reacting azides with alkynes under mild conditions. This reaction is widely used in biomolecule labeling, drug delivery and bioimaging due to its mild conditions, fast reaction speed and good biocompatibility.
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Biotin Azides/Alkynes
Biotin azide or alkyne-containing groups, alkyne, azide group is a highly reactive functional group that can participate in a variety of chemical reactions, especially click chemistry reactions such as CuAAC (copper-catalyzed azide-alkyne cycloaddition) reaction.
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Carbohydrate Azides/Alkynes
Carbohydrate azides/alkynes are carbohydrates containing an azide, and carbohydrate alkynes are carbohydrates containing an alkyne group. The alkyne-azide group is a highly reactive functional group that can participate in a variety of chemical reactions, especially click chemistry reactions such as the CuAAC (copper-catalyzed azide-alkyne cycloaddition) reaction.
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Catalysts, Ligands, Reagents
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Copper-free Click Reaction Reagents
Copper-free click chemistry is a chemical reaction method that can achieve rapid intermolecular connection under mild conditions without the use of toxic copper catalysts. Copper-free click reaction reagents mainly include DBCO (dibenzocyclooctyne) and BCN (benzocyclooctyne) compounds. These reagents can react with azides under copper-free conditions to form stable triazole bonds. They are often used in biomedicine, materials science, and drug development.
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Crosslinker Azides/Alkynes
Cross-linker azides are a class of compounds containing an azide group (N3), and cross-linker alkynes are a class of compounds with an alkynyl (-C≡C-) functional group, which are widely used in drug delivery, biomarkers and other fields.
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Fluorophore Azides/Alkynes
A fluorinated azide or alkyne-containing group, alkyne, is a highly reactive functional group that can participate in a variety of chemical reactions, especially click chemistry reactions such as CuAAC (copper-catalyzed azide-alkyne cycloaddition) reactions.
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PEG Azides/Alkynes
Polyethylene glycol azide/alkyne is a class of polyethylene glycol (PEG) derivatives with azide groups/alkynes. Polyethylene glycol is a commonly used biocompatible polymer, widely used in drug delivery, medical devices, and biomarkers. Introducing azide groups/alkynes into PEG can significantly enhance its application potential in "click chemistry"
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Terminal Alkynes
In the "click chemistry" reaction, terminal alkynes are often combined with azides to form 1,2,3-triazole compounds through the "azide-alkyne" reaction. This process is simple, efficient and highly selective.
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Trialkoxysilane Azides/Alkynes
Trialkoxysilane azides are trialkoxysilanes containing an azide, and trialkoxysilane alkynes are trialkoxysilanes containing an alkyne group. The alkyne-azide group is a highly reactive functional group that can participate in a variety of chemical reactions, especially click chemistry reactions such as the CuAAC (copper-catalyzed azide-alkyne cycloaddition) reaction.
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Tetrazines
Tetrazine is a six-membered heterocyclic compound containing four nitrogen atoms. It has high reactivity, especially in the click reaction with alkynes, which shows rapid, highly selective and stable characteristics. 12 This reactivity of tetrazine makes it widely used in the fields of biomolecule labeling, drug delivery and bioimaging.
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trans-Cyclooctenes (TCO)
Trans-cyclooctene (TCO) is an eight-membered ring structure with a double bond, in which the double bond is in trans (E-type) configuration. This structure enables the TCO portion to undergo efficient bioorthogonal reactions with specific compounds (such as tetrazines). In click chemistry, the TCO group can react with compounds containing an azide group to form a stable 1,2,3-triazole ring structure. This reaction is highly selective and efficient and is widely used in bioimaging, molecular labeling, and bioconjugation fields.
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Direct Dyes
Direct dye is a dye which can be heated and boiled in neutral or weakly alkaline media and dyed without the aid of a modant.
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Acid Dyes
Acid dyes refers to a class of dyes containing acid groups in the dye molecules, also known as anionic dyes.
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Basic Dyes
Basic dyes are a type of textile dye, also known as cationic dyes or salt base dyes.
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Mordant Dyes
Medium dye is a kind of acid dye that needs to be treated with modant to meet the dyeing requirements.
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Azoic Dyes
Azo dyes are a class of synthetic dyes, whose molecular structure contains azo group (-n =N-), widely used in textiles, paints, plastics and rubber coloring.
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Disperse Dyes
Disperse dye is a kind of dye with small molecule and no water-soluble group in structure.It is mainly used for dyeing polyester and its blended fabrics.
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Pigments
Pigment is a powdered substance used for coloring, insoluble in water, oil, resin and other media, but can be evenly dispersed in these media and make the medium colored, with a certain hiding power.
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Dye Intermediates
Dye intermediates refer to various aromatic derivatives used in the production of dyes and organic pigments.
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Vat Dyes
Vat dyes are dyes which are reduced under alkaline conditions to dye the fibers and then oxidized to return to the original insoluble dyes.
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Oil Dyes
Oil dyes are dyes which are soluble in grease,wax or other organic solvents but insoluble in water.
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Stains and Dyes (Other)
Stains and dyes are substances used to impart color to materials, often for scientific, medical, or industrial purposes.
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Methylated Nucleosides
Methylated nucleoside monomers have many functions in biological and medical research. They not only affect gene expression and nucleic acid stability, but also play an important role in drug development and disease diagnosis. These characteristics make them an important target of modern biology. An important tool in technology and drug research.
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Riboses, 2'-Deoxyriboses
Ribose is a component of RNA and is involved in energy metabolism and cell signaling. 2'-deoxyribose is a component of DNA and ensures the stability of DNA and the long-term preservation of genetic information. The main difference between 2'-deoxyribose and ribose is the hydroxyl group on the 2' carbon, which makes DNA more stable than RNA.
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Protected Nucleosides
Protected nucleosides are mainly used in the synthesis of nucleic acids and their derivatives in chemical and biological research. The role of the protecting group is to prevent the active groups of the nucleoside (such as hydroxyl, amino, etc.) from undergoing undesirable reactions in chemical reactions, thereby improving the selectivity and yield of the synthesis. They are often used in nucleic acid synthesis, such as the synthesis of DNA or RNA, to ensure that specific reaction steps do not damage the structure of the synthesized part. The protecting group will be removed after the synthesis is completed, restoring the active groups of the nucleoside and ensuring the functionality of the final product.
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Nucleoside Phosphoramidites
Phosphoramidite monomers are widely used in the chemical and pharmaceutical fields. In the chemical field, phosphoramidite monomers are mainly used to prepare polymer materials such as polyamide and polyimide. In the pharmaceutical field, especially in the fields of molecular biology and genetics, phosphoramidite monomers also play an important role. For example, in the synthesis of DNA and RNA, phosphoramidite monomers are an important raw material. They can react with amine groups to form phosphoramide bonds, connect deoxyribose or ribose to bases, and thus construct DNA and RNA molecules.
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Base Modified Nucleosides and Nucleotides
Base-modified nucleosides and nucleotides play important roles in gene regulation, cell signaling, molecular recognition, and disease mechanisms, and are crucial for the maintenance and regulation of life processes.
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Amine Protection
In peptide synthesis, especially in solid-phase synthesis and liquid-phase synthesis, the amino group of the amino acid needs to react with the carboxyl group to form a peptide bond. The amino protecting group can protect the amino group from interference from other reactants, thereby achieving selective synthesis of the target sequence.
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Amino Acid Derivatives
Amino acid derivatives refer to new compounds obtained by chemically modifying the side chains, amino groups or carboxyl groups of natural amino acids. Common modifications include substitution reactions, acylation, phosphorylation, methylation, etc.
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Unnatural Amino Acid Derivatives
Non-natural amino acid derivatives refer to amino acids that do not exist in nature or are present in very small amounts. They are usually obtained by artificial synthesis or chemical modification of natural amino acids. These derivatives have diverse side chain groups and unique chemical properties and can be introduced into engineered proteins through genetic codon expansion, metabolic labeling, or protein full/semi-synthesis technology. They are widely used in biochemistry, drug development, materials science and other fields.
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mPEG (Methyl Polyethylene Glycols)
mPEG refers to a polymer formed by introducing methyl (-CH₃) side groups through chemical modification based on polyethylene glycol. mPEG has good water solubility, wettability, lubricity and physiological inertness, and is mild and non-irritating to the human body. It has important application value in many fields such as drug delivery, cosmetics, food and medical devices.
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Monofunctional PEG and Oligoethylene Glycols
Monofunctional polyethylene glycol (PEG) contains a single chemically reactive end and is commonly used for PEGylation, surface grafting, and nanoparticle coating. Monofunctional PEG is commonly used in bioconjugation, surface functionalization, and nanoparticle coating. Oligopolyethylene glycol (such as PEG-2, PEG-4) is mainly used as a solvent and penetration enhancer to promote the dissolution of active ingredients, improve stability and solubility, enhance the permeability and absorption of oral drugs, and thus improve bioavailability.
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Heterobifunctional PEG and Oligoethylene Glycols
Heterobifunctional polyethylene glycol (PEG) has different functional groups at each end of the PEG chain. These linkers allow selective conjugation between two different molecules or surfaces. It is widely used in bioconjugation reactions to connect different molecules or surfaces to achieve specific chemical and biological functions. Oligopolyethylene glycol (such as PEG-2, PEG-4) is mainly used as a solvent and penetration enhancer to promote the dissolution of active ingredients, improve stability and solubility, enhance the permeability and absorption of oral drugs, and thus improve bioavailability.
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PEG Oligomers
Polyethylene glycol oligomers are low molecular weight polymers formed by polymerization of ethylene glycol molecules. They have short molecular chains and relatively low molecular weight, so they have some special physical and chemical properties. Polyethylene glycol oligomers have good solubility and permeability, can form stable solutions in water, and easily interact with other substances. They are widely used in biomedicine, cosmetics, and food industries.
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PEG Polymers
Polyethylene glycol (PEG), also known as polyethylene oxide (PEO) or polyoxyethylene (POE), refers to oligomers or polymers of ethylene oxide. Polyethylene glycol has excellent lubricity, moisturizing and dispersibility, and can be used as a softener and antistatic agent. It is widely used in cosmetics, pharmaceuticals, chemical fibers, rubber, plastics, papermaking, paints, electroplating, pesticides, metal processing and food processing industries.
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Homobifunctional PEG and Oligoethylene Glycols
Homobifunctional polyethylene glycol refers to a PEG molecule with two identical reactive groups. This structure enables it to form crosslinks or connections with other molecules or materials, and is often used to construct multifunctional nanocarriers or crosslinked polymers. Oligopolyethylene glycol (such as PEG-2 and PEG-4) is mainly used as a solvent and permeation enhancer to promote the dissolution of active ingredients, improve stability and solubility, enhance the permeability and absorption of oral drugs, and thus improve bioavailability.
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Heterobifunctional Cross-Linkers
Heterobifunctional crosslinkers have different reactive groups at both ends. These crosslinkers can not only couple molecules with their respective target functional groups in a single step, but also in a sequential (two-step) manner, minimizing unwanted aggregation or self-coupling. They are often used in biochemical and biomedical research, especially in protein modification, protein coupling, and protein interaction studies.
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Homobifunctional Cross-Linkers
Homobifunctional crosslinkers contain two or more identical reactive groups in their structure. These reactive groups can react with the molecules to be crosslinked to form a crosslinked structure. Since the reactive groups of these crosslinkers are the same, they can react with the same type of reactive groups.
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Photo-reactive Crosslinkers
Photoreactive crosslinkers are a class of compounds that can initiate chemical crosslinking reactions by light irradiation. Aryl azides (AZs), benzophenones (BPs), diaziridines (DAs) and 2-aryl-5-carboxytetrazoles (ACTs). Under ultraviolet excitation of a specific wavelength, the corresponding intermediates are nitrene, diradical, carbene and carboxynitrile imine. Among them, carbene-mediated photoaffinity labeling is widely used in drug target recognition.
Conjugation Chemistry/Click Chemistry
- Aldehyde Reactive Fluorophores and Labels
- Amino Acid Azides/Alkynes
- Trialkoxysilane Azides/Alkynes
- Carbohydrate Azides/Alkynes
- Catalysts, Ligands, Reagents
- Copper-free Click Reaction Reagents
- Fluorophore Azides/Alkynes
- Biotin Azides/Alkynes
- Nucleoside Azides/Alkynes
- Crosslinker Azides/Alkynes
- PEG Azides/Alkynes
- Terminal Alkynes
- Tetrazines
- Azides
- trans-Cyclooctenes (TCO)
Nucleic Acid Chemistry
- Methylated Nucleosides
- Protecting Agents for Hydroxy and Amino Groups
- Phosphorylating Agents, Phosphorothioating Agents
- Coupling Activators, Condensing Agents
- Riboses, 2'-Deoxyriboses
- Sulfur Transfer Reagents
- Protected Nucleosides
- Nucleoside Phosphoramidites
- Peptide Nucleic Acid (PNA) Monomers
- Base Modified Nucleosides and Nucleotides
- 2'-O-Methylribonucleosides
Bioconjugation
- Enzyme Cleavable Linkers (Cleave Motif)
- Biotins, Streptavidins
- Functionality Creating Reagents
- Functional Group Blocking Reagents
- Heterobifunctional Cross-Linkers
- PEGylation Reagents and PEG Spacers
- Zero-length Crosslinkers
- Albumin Binding Modification Reagents
- Homobifunctional Cross-Linkers
- Copper-free Click Reaction Reagents
- Photo-reactive Crosslinkers
- N-Terminal Cysteine Residue-specific Conjugation Reagents
Drug Delivery Systems (DDS)
- Prodrug Ingredients
- Natural Polymers (for DDS)
- Monomers for Synthetic Polymers (for DDS)
- Polyethyleneglycols (PEG) (for DDS)
- PEGylation Reagents (for DDS)
- Cyclodextrins (for DDS)
- Drug Delivery Systems (DDS) Research Reagents (Others)
- Phospholipids (for DDS)
- Lipids (Other) (for DDS)
- Synthetic Polymers (for DDS)
- Chelating Agents (for DDS)
Nucleic Acid Chemistry
- Methylated Nucleosides
- Protecting Agents for Hydroxy and Amino Groups
- Phosphorylating Agents, Phosphorothioating Agents
- Coupling Activators, Condensing Agents
- Riboses, 2'-Deoxyriboses
- Sulfur Transfer Reagents
- Protected Nucleosides
- Nucleoside Phosphoramidites
- Peptide Nucleic Acid (PNA) Monomers
- Base Modified Nucleosides and Nucleotides
- 2'-O-Methylribonucleosides