Linkers and Crosslinkers

Cross-linkers are molecules with two or more reactive ends that can be chemically linked to specific functional groups (primary amines, sulfhydryls, etc.) on proteins or other molecules. This technique, often referred to as bioconjugation when used with proteins and other biomolecules, is an important component of many proteomics methods, including the creation of detectable probes for western blotting and ELISA, as well as strategies to study protein structure and interactions.