Synthetic Reagents

Acids

Acids [Synthetic Reagents] are acidic compounds commonly used in chemical synthesis, which have been widely used in organic synthesis, analytical chemistry, catalytic reactions, etc.

Bases

Bases play a vital role in many organic reactions, especially in deprotonation, dehydration, removal of halohydrates, acid-base neutralization, etc.

Benzyne Precursors

The synthetic precursors of phenylenes are generally styrene and its derivatives, which can be converted to phenylenes by dehydrogenation.

Naphthalyne Precursors

Naphthalene is a simple polycyclic aromatic hydrocarbon (PAH) consisting of two fused benzene rings.Naphthalene is a simple polycyclic aromatic hydrocarbon (PAH) consisting of two fused benzene rings.

Pyridyne Precursors

Pyridine Precursors refer to chemical compounds or intermediates that serve as building blocks for the synthesis of pyridine and its derivatives. Pyridine itself is a six-membered aromatic nitrogen heterocycle, and its derivatives are important in pharmaceuticals, agrochemicals, and materials science.

Quinolyne Precursors

Quinoline precursors typically involve compounds with aromatic rings and nitrogen atoms.

Aryne Precursors (Other), Related Compounds

Reagents for the Generation of Arynes

Reagents for the Generation of Arynes are highly reactive and can undergo various nucleophilic addition reactions, such as with alkyl groups, carbon nucleophiles, or oxygen nucleophiles to form substituted aromatic products.

Olefination

New olefins or olefin derivatives are generated in organic synthesis and are often used in petrochemical and pharmaceutical synthesis.

Carbon Monoxide Surrogate Reagents

Carbon Monoxide Surrogate Reagents can replace CO for CC bond formation, such as acyl halides and carbamates, which are safer and more controllable in many classical reactions.

Cross-coupling Reaction using Transition Metal Catalysts

Cross-coupling Reaction using Transition Metal Catalysts is the coupling reaction of two different organic substrates (usually halogenated hydrocarbons or molecules containing active groups) through a transition metal catalyst. These reactions involve the coordination of metal centers with organic substrates, activation, and eventually carbon -carbon bond formation.

C-C Bond Formation (Other)

The CC Bond Formation reagent is able to join two carbon atoms together to form a new carbon-carbon bond.

Weinreb Amides

Weinreb Amides is a very valuable intermediate in organic chemistry, reacting with nucleophiles and organometre-metal reagents.

Bromination

Bromination is the chemical reaction in which bromine element (Br) is added to a molecule to form a bromide.

Chlorination

In organic synthesis, chlorination reagents are widely used in chlorination reactions, of which the most common chlorination reactions are the generation of chlorinated hydrocarbons, esterification, acylation and so on.

Iodination

In synthesis, compounds in which iodine atoms are introduced are often used in drug synthesis, molecular labeling, and radiolabelling.

Alkyl Transfer

Alkyl Transfer [Synthetic Reagents] is a reaction that transfers an alkyl group (-R) to a molecule. Alkyl transfer reaction has a wide range of applications in synthetic chemistry, especially in synthetic drugs, pesticides, plastics and other organic compounds.

Alkylation (Esterification)

Alkylation (Esterification) is a class of anhydrides,acid chlorides,organic acids,isocyanates and other organic compounds used to synthesize ester compounds.

Amination

Amination is the introduction of an amine group (-NH ₂) into a molecule, often used to synthesize amines.

Azidation, Diazo Transfer

Boration

Boration [Synthetic Reagents] is the introduction of a B atom or its compounds into a molecule in a chemical reaction, usually by introducing a boron group (eg-BR,-B(OH)₂,etc.) into the structure of an organic molecule.

C-H Bond Activation Reaction

CH Bond Activation Reaction refers to the chemical method to make the carbon-hydrogen bond (CH bond) more active, so that it can participate in further chemical reactions, and has important applications in organic synthesis, especially in highly selective and efficient functionalization reactions.

C-S Bond Formation

Cs Bond Formation is the bonding of C and S atoms to form a carbon-sulfur (CS) single bond. Commonly used in the synthesis of mercaptan, thioether, thioester, thioether drugs, functional materials and so on.

C-Se Bond Formation

C-se Bond Formation connects C and Se atoms to form carbon-selenium bond (C-Se), which is commonly used in the synthesis of organoselenium compounds, functional materials, drug molecules, etc.

Cyanation

Cyanide reagent refers to the introduction of -CN group in synthesis, which is often used in pharmaceutical, pesticide, plastic and dye fields.

Ethynylation

By selecting appropriate ethyl reagents and optimizing reaction conditions, ethyl groups can be effectively introduced, molecular structure can be changed, and molecular properties can be improved.

Formylation

Formylation is used to introduce formyl groups (CHO) into organic chemical reactions and is commonly used in the preparation of aldehydes, drug molecules and functional materials.

Guanidinylation

By introducing guanidine groups into molecules, guanidylation can significantly alter the chemical and biological properties of molecules. It is often used in drug synthesis, catalytic reactions or biomolecular modification.

Mitsunobu Reaction

Mitsunobu reactions can convert alcohols into various other functional groups, such as esters, ethers, and azides, often with high stereoselectivity. It is often used in the synthesis of drugs and natural products.

Nitration

Introduction of nitro (-NO2) into organic compound molecules.

Phosphorylation

Phosphorylation is the synthesis of phosphorylation products such as phosphate esters or phosphoamides, which are commonly used for protein phosphorylation, drug design and molecular labeling.

Vinylation

The introduction of vinyl in synthesis is often used in the synthesis of polymers, drugs and materials.

C-X(Non-Halogen) Bond Formation (Other)

CX (Non-Halogen) Bond Formation involves a wide range of reaction types, including nucleophilic substitution reaction, addition reaction, reduction reaction, insertion reaction, etc.

Arylation

Arylation is the introduction of aromatic groups (such as phenyl groups) into other molecules.

EDTA Derivatives

EDTA Derivatives are common chelators used in specific metal ion complexation, separation, detection, drug delivery and other applications.

Chelation/Complexation Compounds (Other)

Other chelating/complexing compounds formed by a coordination bond between the central metal ion and the ligand.

Calixarenes

Calixarene is a class of macrocyclic compounds composed of methylene bridged phenol units,commonly used in supramolecular chemistry.

Crown Ethers

The oxygen atoms in crown ether molecules can form coordination bonds with metal ions, and crown ether has a wide range of applications in chemistry, materials science and molecular recognition.

Cyclodextrins

Cyclodextrins are cyclic oligosaccharides formed from glucose molecules connected by α-1,4 glucoside bonds, which are widely used in drug delivery, food, cosmetics and environmental protection.

Active Esters, Additives

Carbodiimides

Carbodiimide coupling agent is a kind of compound containing N=C=N functional group, which is mainly used to activate carboxylic groups and promote the formation of amides and esters.

Carbonyldiimidazole Derivatives

Carbonyldiimidazole Derivatives can promote acylation and peptide synthesis.

Phosgene Derivatives

Phosgene Derivatives are compounds derived from phosgene, often used in the synthesis of acyl chloride, peptide synthesis, esterification and isocyanate.

Phosphonium Salts, Uronium Salts, Formamidinium Salts

Triflate Formation

Triflate Formation usually involves the reaction of alcohols with trifluoromethanesulfonic acid or trifluoromethanesulfonic acid esterification reagents, and the resulting triflesulfonic acid ester is widely used in organic synthesis as an excellent leaving group or intermediate.

Coupling Reagents (Other)

Other coupling reagents used to form carbon-carbon bonds to build complex organic molecules.

Fluorination

Fluorinated reagents are used as fluorination sources to introduce fluorine atoms in organic synthesis.

Difluoromethylation

Difluoromethyl group is a kind of functional group with special electronic properties, which is widely used in organic synthesis, especially in pharmaceutical chemistry, pesticide synthesis and material science.

Trifluoromethylation

Because of its unique electronic properties (strong electron absorption) and stability, trifluoromethyl groups are widely used in drug synthesis, pesticide chemistry and materials science.

Fluorination Reagents (Other)

Other fluorination reagents used to introduce fluorine atoms in organic synthesis.

Trifluoromethylthiolation

The introduction of trifluoromethyl sulfur group can regulate the electronic properties of the molecule, improve its stability and biological activity.

Chromates

Chromate oxidizer is a kind of strong oxidizer based on chromium element, which is often used in oxidation reaction of organic synthesis.

Hypervalent Iodine

Hypervalent Iodine is a green, efficient and multi-functional oxidizer, which is widely used in organic synthesis, material chemistry and industrial synthesis.

Perchlorates

Perchlorates contains ClO₄⁻.It is strongly oxidizing and is often used as an oxidizing agent.

Sulfur Oxides

Sulfur Oxides have strong oxidizing properties and are often used in organic oxidation reactions.

Oxidants (Other)

Other oxidizing agents used in reactions in which organic matter introduces oxygen or dehydrogenates.

N-Oxides

An oxidizing agent containing NO bonds, commonly used in oxidation-activated substrates, carboxylation, allylation, aldehyylation.

Ammonium Salts

Ammonium salt phase transfer catalyst is a kind of catalyst which can promote the transfer of reactants from aqueous phase to organic phase, thus speeding up the reaction rate of heterophase system.

Phosphonium Salts

When Phosphonium Salts are used as phase transfer catalyst, they facilitate the interaction of reactants in the two-phase system, especially when nucleophilic salts, esterification, halogenation are involved in synthesis.

Deprotecting Reagents

Deprotecting Reagents are reagents used in chemical synthesis to remove chemical protective groups.

Protecting and Derivatizing Reagents

Protecting and Derivatizing Reagents control the selectivity of the whole reaction, improve the yield and avoid side reactions by protecting the active group.

Radical Generators

Radical Generators play an important role in many chemical reactions, especially in the fields of free radical polymerization, organic synthesis, and photocuring reactions.

Stable Radicals

Common stable free radicals include nitrogen oxide free radicals, aromatic free radicals, acylazide free radicals, etc., which are often used to control polymerization, improve synthesis efficiency and improve material properties.

Boranes

Boranes Reduction is a class of chemical reducing agents containing boron (B) element, which is widely used in the reduction reaction of organic synthesis, reducing aldehyde, ketone, ester, nitroso and other functional groups.

Borohydrides

Borohydrides [Reduction] is a very important class of reducing agents in organic synthesis, widely used in reducing aldehydes, ketones, nitro, nitroso, esters and other compounds.

Reduction Reagents (Other)

A substance that provides electrons or hydrogen atoms to reduce other chemicals.

Silanes

Silane reducing agents are very effective reducing agents, especially suitable for selective reduction of various functional groups in organic synthesis.