Nucleoside Phosphoramidites
Phosphoramidite monomers are widely used in the chemical and pharmaceutical fields. In the chemical field, phosphoramidite monomers are mainly used to prepare polymer materials such as polyamide and polyimide. In the pharmaceutical field, especially in the fields of molecular biology and genetics, phosphoramidite monomers also play an important role. For example, in the synthesis of DNA and RNA, phosphoramidite monomers are an important raw material. They can react with amine groups to form phosphoramide bonds, connect deoxyribose or ribose to bases, and thus construct DNA and RNA molecules. Secondly, phosphoramidite monomers can also be used in gene therapy, such as synthetic gene vectors (plasmids and viral vectors).