Classified by application
Signaling Pathways
-
Anti-infection
- Anti-infection
- Antibiotic
- Arenavirus
- Bacterial
- Beta-lactamase
- CMV
- Dengue virus
- EBV
- Enterovirus
- Filovirus
- Flavivirus
- Fungal
- HBV
- HCV
- HCV Protease
- HIV
- HIV Protease
- HPV
- HSV
- Influenza Virus
- Orthopoxvirus
- Parasite
- Penicillin-binding protein (PBP)
- RABV
- Reverse Transcriptase
- RSV
- SARS-CoV
- TMV
- Virus Protease
- VSV
- Antibody-drug Conjugate/ADC Related
- Apoptosis
- Autophagy
-
Cell Cycle/DNA Damage
- Cell Cycle/DNA Damage
- Antifolate
- APC
- ATF6
- ATM/ATR
- Aurora Kinase
- Casein Kinase
- CDK
- CDKL
- Checkpoint Kinase (Chk)
- ClpP
- CRISPR/Cas9
- Cyclin G-associated Kinase (GAK)
- Deubiquitinase
- DNA Alkylator/Crosslinker
- DNA Stain
- DNA-PK
- DNA/RNA Synthesis
- Early 2 Factor (E2F)
- Endonuclease
- Eukaryotic Initiation Factor (eIF)
- FKBP
- Folate Receptor (FR)
- G-quadruplex
- Haspin Kinase
- HDAC
- Hec1
- HSP
- IRE1
- Kinesin
- LIM Kinase (LIMK)
- MARK
- MASTL
- Microtubule/Tubulin
- Mps1
- NEKs
- Nucleoside Antimetabolite/Analog
- p97
- PAK
- PARP
- PDI
- PERK
- Polo-like Kinase (PLK)
- Poly(ADP-ribose) Glycohydrolase (PARG)
- PPAR
- RAD51
- ROCK
- Separase
- Sirtuin
- SRPK
- STK33
- SWI/SNF Complex
- Telomerase
- TOPK
- Topoisomerase
- Wee1
- YB-1
- Cytoskeleton
-
Epigenetics
- Epigenetics
- AMPK
- Aurora Kinase
- DNA Methyltransferase
- Epigenetic Reader Domain
- Glycosyltransferase
- HDAC
- Histone Acetyltransferase
- Histone Demethylase
- Histone Methyltransferase
- HuR
- JAK
- Methionine Adenosyltransferase (MAT)
- METTL3
- MicroRNA
- PARP
- PKC
- Protein Arginine Deiminase
- SF3B1
- Sirtuin
- Small Interfering RNA (siRNA)
- TET Protein
- WDR5
-
GPCR/G Protein
- GPCR/G Protein
- 5-HT Receptor
- Adenosine Receptor
- Adenylate Cyclase
- Adrenergic Receptor
- Amylin Receptor
- Angiotensin Receptor
- Apelin Receptor (APJ)
- Arf Family GTPase
- Arrestin
- Bombesin Receptor
- Bradykinin Receptor
- Cannabinoid Receptor
- CaSR
- CCR
- CGRP Receptor
- Chemerin Receptor
- Cholecystokinin Receptor
- CRFR
- CRTH2 (GPR44)
- CXCR
- Dopamine Receptor
- EBI2/GPR183
- Endothelin Receptor
- Formyl Peptide Receptor (FPR)
- Free Fatty Acid Receptor
- G protein-coupled Bile Acid Receptor 1
- G Protein-coupled Receptor Kinase (GRK)
- G2A (GPR132)
- GCGR
- GHSR
- GLP Receptor
- GnRH Receptor
- GPR109A
- GPR119
- GPR139
- GPR171
- GPR35
- GPR4
- GPR52
- GPR55
- GPR6
- GPR68
- GPR84
- GPR88
- Guanylate Cyclase
- Histamine Receptor
- Hydroxycarboxylic Acid Receptor (HCAR)
- ICMT
- Kisspeptin Receptor
- Leukotriene Receptor
- LPL Receptor
- mAChR
- Mas-related G-protein-coupled Receptor (MRGPR)
- MCHR1 (GPR24)
- Melanocortin Receptor
- Melatonin Receptor
- mGluR
- Motilin Receptor
- Neurokinin Receptor
- Neuromedin U Receptor (NMUR)
- Neuropeptide B/W Receptor
- Neuropeptide FF Receptor
- Neuropeptide Y Receptor
- Neurotensin Receptor
- Opioid Receptor
- Orexin Receptor (OX Receptor)
- Orphan Receptor
- Oxytocin Receptor
- P2Y Receptor
- PACAP Receptor
- Platelet-activating Factor Receptor (PAFR)
- Prostaglandin Receptor
- Protease Activated Receptor (PAR)
- PTHR
- Ras
- RGS Protein
- RXFP Receptor
- Secretin Receptor
- Somatostatin Receptor
- Succinate Receptor 1
- Taste Receptor
- Trace Amine-associated Receptor (TAAR)
- TSH Receptor
- Urotensin Receptor
- Vasopressin Receptor
-
Immunology/Inflammation
- Immunology/Inflammation
- AIM2
- ALCAM/CD166
- AP-1
- Arginase
- Aryl Hydrocarbon Receptor
- BCL6
- C-type Lectin-like Receptors (CTLRs)
- CCR
- CD19
- CD2
- CD20
- CD22
- CD276/B7-H3
- CD28
- CD3
- CD38
- CD44
- CD47
- CD6
- CD73
- CD74
- Complement System
- COX
- CRTH2 (GPR44)
- CTLA-4
- CX3CR1
- CXCR
- Cyclic GMP-AMP Synthase
- Cyclophilin
- DOCK
- FAP
- FKBP
- FLAP
- Galectin
- Glucocorticoid Receptor
- Glycoprotein VI
- Histamine Receptor
- Human leukocyte immunoglobulin (Ig)-like receptors (LILR)
- IFNAR
- IKZF Family
- Interleukin Related
- IRAK
- Kallikrein
- LAG-3
- Macrophage migration inhibitory factor (MIF)
- Mesothelin
- MHC
- Mucin
- MyD88
- Nectin-4
- NO Synthase
- NOD-like Receptor (NLR)
- NTPDase
- Nuclear Factor of activated T Cells (NFAT)
- P-selectin
- PD-1/PD-L1
- PGE synthase
- PSMA
- Pyroptosis
- Reactive Oxygen Species
- Salt-inducible Kinase (SIK)
- SOD
- SphK
- STING
- Thrombopoietin Receptor
- Tim3
- Toll-like Receptor (TLR)
- TREM receptor
- TROP2
- VAP-1
- JAK/STAT Signaling
-
MAPK/ERK Pathway
- MAPK/ERK Pathway
- ERK
- JNK
- KLF
- MAP3K
- MAP4K
- MAPKAPK2 (MK2)
- MEK
- Mixed Lineage Kinase
- MNK
- p38 MAPK
- Raf
- Ras
- Ribosomal S6 Kinase (RSK)
-
Membrane Transporter/Ion Channel
- Membrane Transporter/Ion Channel
- Amino acid Transporter
- Anion Exchangers
- Apical Sodium-Dependent Bile Acid Transporter
- Aquaporin
- ASCT
- ATP Synthase
- BCRP
- Calcium Channel
- CFTR
- Chloride Channel
- CRAC Channel
- CRM1
- EAAT
- EHD Protein
- FATP
- Ferroportin
- GABA Receptor
- GLUT
- GlyT
- HCN Channel
- iGluR
- Monoamine Transporter
- Monocarboxylate Transporter
- Na+/Ca2+ Exchanger
- Na+/H+ Exchanger (NHE)
- Na+/HCO3- Cotransporter
- Na+/K+ ATPase
- nAChR
- NKCC
- OAT
- P-glycoprotein
- P2X Receptor
- Piezo Channel
- Potassium Channel
- Proton Pump
- SGLT
- Sodium Channel
- Sodium Phosphate Cotransporter
- Synaptic Vesicle Proteins
- TRP Channel
- URAT1
- Urea Transporter
- VDAC
- WNK Kinase
-
Metabolic Enzyme/Protease
- Metabolic Enzyme/Protease
- 11β-HSD
- 15-PGDH
- 17β-HSD
- 5 alpha Reductase
- Acetolactate Synthase (ALS)
- Acetyl-CoA Carboxylase
- Acetyl-CoA Carboxylase
- Acetyl-CoA synthetase
- Acyltransferase
- ADAMTS
- Adenosine Deaminase
- Adenosine Kinase
- Adiponectin Receptor
- Aldehyde Dehydrogenase (ALDH)
- Aldehyde Oxidase (AO)
- Aldose Reductase
- Amine N-methyltransferase
- Aminoacyl-tRNA Synthetase
- Aminopeptidase
- Aminotransferases (Transaminases)
- Amylases
- Angiotensin-converting Enzyme (ACE)
- ANGPTL
- Apolipoprotein
- Arginase
- ATGL
- ATP Citrate Lyase
- Carbamoyl Phosphate Synthetase (CPS)
- Carbonic Anhydrase
- Carboxylesterase
- Carboxypeptidase
- Carnosine-cleaving Enzyme
- Cathepsin
- Ceramidase
- CETP
- COMT
- Creatine Kinase
- Cryptochrome
- Cytochrome P450
- DAGL
- DGK
- Dihydrofolate reductase (DHFR)
- Dihydroorotate Dehydrogenase
- Dipeptidyl Peptidase
- Dopamine β-hydroxylase
- Drug Metabolite
- E1/E2/E3 Enzyme
- Elastase
- ELOVL
- Endogenous Metabolite
- Enolase
- Enteropeptidase
- Epoxide Hydrolase
- FAAH
- FABP
- Factor VIIa
- Factor VIII
- Factor Xa
- Factor XI
- Farnesyl Transferase
- Fat Mass and Obesity-associated Protein (FTO)
- Fatty Acid Synthase (FASN)
- FBPase
- FOXO
- Furin
- FXR
- GGTase
- GHR
- Glucokinase
- Glutamate Dehydrogenase (GLDH)
- Glutamate Dehydrogenase (GLDH)
- Glutaminase
- Glutathione Peroxidase
- Glutathione Reductase
- Glutathione S-transferase
- Glyoxalase (GLO)
- GSNOR
- HCV Protease
- Hexokinase
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- HMG-CoA Reductase (HMGCR)
- Hormone-Sensitive Lipase (HSL)
- HPPD
- HSP
- IDE
- Indoleamine 2,3-Dioxygenase (IDO)
- Isocitrate Dehydrogenase (IDH)
- Ketohexokinase
- KMO
- Lactate Dehydrogenase
- LDLR
- Lipase
- Liposome
- Lipoxygenase
- LOX-1
- LXR
- MAGL
- MALT1
- MetAP
- Methionine Adenosyltransferase (MAT)
- Methylenetetrahydrofolate Dehydrogenase (MTHFD)
- Microsomal Triglyceride Transfer Protein (MTP)
- Mineralocorticoid Receptor
- Mitochondrial Metabolism
- MMP
- N-myristoyltransferase
- NADPH Oxidase
- NAMPT
- NEDD8-activating Enzyme
- Neprilysin
- Neuropathy Target Esterase (NTE)
- Ornithine decarboxylase (ODC)
- Oxidative Phosphorylation
- PAI-1
- PANK
- PCSK9
- PDHK
- PDI
- PEPCK
- PGC-1α
- Phosphatase
- Phosphatidylcholine Transfer Protein (PC-TP)
- Phosphodiesterase (PDE)
- Phosphoglycerate Dehydrogenase (PHGDH)
- Phosphoglycerate Kinase (PGK)
- Phospholipase
- Phosphomannose Isomerase (PMI)
- Photosystem II
- PI5P4K
- PPAR
- Procollagen C Proteinase
- Prolyl Endopeptidase (PREP)
- Proteasome
- Proteolytic Enzyme
- Protoporphyrinogen IX oxidase
- Pyruvate Carboxylase (PC)
- Pyruvate Kinase
- Pyruvate Oxidase
- Quinone Reductase
- RAR/RXR
- Reactive Oxygen Species
- Renin
- REV-ERB
- ROR
- Ser/Thr Kinase
- Ser/Thr Protease
- Serine Racemase (SR)
- SGK
- SHMT
- Sialyltransferase
- Stearoyl-CoA Desaturase (SCD)
- Steroid Sulfatase
- Succinate Dehydrogenase
- Thrombin
- Tissue Factor Pathway Inhibitor (TFPI)
- Transketolase
- TrxR
- Tryptophan Hydroxylase
- Tyrosinase
- Tyrosine Hydroxylase
- UGT
- Xanthine Oxidase
- β-glucuronidase
-
Neuronal Signaling
- Neuronal Signaling
- 5-HT Receptor
- AAK1
- Adenosine Kinase
- Adrenergic Receptor
- Amyloid-β
- Aromatic L-amino acid decarboxylase (AADC)
- Beta-secretase
- Calcineurin
- Calcium Channel
- CaMK
- Cannabinoid Receptor
- CGRP Receptor
- Cholecystokinin Receptor
- Cholinesterase (ChE)
- COMT
- Dihydroceramide Desaturase 1 (DES1)
- Dopamine Receptor
- Dopamine Transporter
- FAAH
- GABA Receptor
- Glucosylceramide Synthase (GCS)
- GlyT
- GPR119
- GPR139
- GPR55
- Histamine Receptor
- Huntingtin
- iGluR
- Imidazoline Receptor
- Legumain
- mAChR
- MCHR1 (GPR24)
- Melanocortin Receptor
- Melatonin Receptor
- mGluR
- Monoamine Oxidase
- nAChR
- Neurokinin Receptor
- Neuropeptide Y Receptor
- Neurotensin Receptor
- Notch
- OGA
- OGT
- Olfactory Receptor
- OLIG2
- Opioid Receptor
- Orexin Receptor (OX Receptor)
- PINK1/Parkin
- Serotonin Transporter
- Sigma Receptor
- Somatostatin Receptor
- Tau Protein
- Transthyretin (TTR)
- Trk Receptor
- TRP Channel
- α-synuclein
- γ-secretase
- NF-κB
- PI3K/Akt/mTOR
- PROTAC
-
Protein Tyrosine Kinase/RTK
- Protein Tyrosine Kinase/RTK
- Ack1
- Anaplastic lymphoma kinase (ALK)
- Bcr-Abl
- BMX Kinase
- BRK
- Btk
- c-Fms
- c-Kit
- c-Met/HGFR
- Discoidin Domain Receptor
- DYRK
- EGFR
- Ephrin Receptor
- FAK
- FGFR
- FLT3
- GDNF Receptor
- IGF-1R
- Insulin Receptor
- Itk
- JAK
- PDGFR
- Pyk2
- RET
- ROS Kinase
- SHP2
- Src
- Syk
- TAM Receptor
- Tie
- Trk Receptor
- VEGFR
- Stem Cell/Wnt
-
TGF-beta/Smad
- TGF-beta/Smad
- PKA
- PKC
- ROCK
- TGF-beta/Smad
- TGF-β Receptor
- Vitamin D Related/Nuclear Receptor
- Others