Peptide/Protease Linker
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Chemically labile linkers often have limited plasma stability, leading to premature drug release. In this regard, as an alternative strategy, enzymatically cleavable linkers have achieved clinical success in controlling drug release. Unlike chemically labile linkers, enzymatically cleavable linkers exploit the high concentration of unique hydrolases in cellular compartments to degrade peptides and carbohydrates.
Peptide/Protease Linker
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