Alkyne

In click chemistry, one of the most classic reactions is the copper-catalyzed [3+2] cycloaddition reaction of alkynes with imines (or other reaction partners) to form a five-membered ring. This reaction is known for its high efficiency and selectivity, and is an ideal method for building complex molecules. Alkynes can also react with a variety of reactants (such as azides, aldehydes, ketones, etc.) to generate stable compounds. These reactions usually have high yields and mild conditions. In biochemical research, alkynes can be used to construct biomarkers.