LNP

LNP, the full name of Lipid Nanoparticle, is a lipid vesicle with a uniform lipid core, and its diameter is usually around 100 nm. This unique structure and size give it unique physical and chemical properties, which can effectively encapsulate and protect nucleic acid drugs, such as mRNA, siRNA, antisense oligonucleotides, etc., and transport them to target tissues or cells through the blood circulation system. Classic LNP is mainly composed of ionizable cationic lipids, PEGylated lipids, cholesterol and neutral auxiliary lipids.