2-Amino-3-chlorobenzonitrile

CAS No. 53312-77-9
Cat. No. CS-W008285
Purity≥97%
MDL No.MFCD03425881

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 53312-77-9

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2-Amino-3-chlorobenzonitrile features a strategically positioned amino group and chloro substituent on a nitrile-bearing benzene ring, enabling direct incorporation into pharmaceutical intermediates. The electron-rich amine facilitates nucleophilic coupling reactions, while the chloro handle permits palladium-catalyzed cross-coupling transformations under standard conditions. This scaffold delivers high functional group tolerance and stability during process development workflows.

Application

2-Amino-3-chlorobenzonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds via cyclization reactions. Its ortho-directed reactivity facilitates efficient functionalization, while the amino and nitrile groups offer complementary handles for further derivatization. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthetic campaigns in API development.

General Information

CAS No. 53312-77-9
Cat. No. CS-W008285
Purity ≥97%
MDL No. MFCD03425881
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅ClN₂
Molecular Weight 152.58
Synonym(s) benzonitrile, 2-amino-3-chloro-
SMILES NC1=C(C#N)C=CC=C1Cl

Computational Chemistry Data

TPSA 49.81
LogP 1.79388
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 3439
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H302+H312-H315-H319-H331-H335
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2-Amino-3-chlorobenzonitrile sigma2-Amino-3-chlorobenzonitrile manufacturer2-Amino-3-chlorobenzonitrile price2-Amino-3-chlorobenzonitrile structure2-Amino-3-chlorobenzonitrile SDSbuy 2-Amino-3-chlorobenzonitrile2-Amino-3-chlorobenzonitrile supplier2-Amino-3-chlorobenzonitrile uses2-Amino-3-chlorobenzonitrile molecular weightprice of 2-Amino-3-chlorobenzonitrile2-Amino-3-chlorobenzonitrile chemical name formula of 2-Amino-3-chlorobenzonitrile

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Amino-3-chlorobenzonitrile

CAS No. 53312-77-9

Recommended Products