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CS-W001157 4
Total: USD 88.00

(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide Cinacalcet Impurity

  • CAS No. 1005450-55-4

  • Cat. No. CS-0229383
  • Molecule weight371.40
  • Purity≥98%
  • MDL No.MFCD18207041

*For research and further manufacturing use only, not for direct human use.

(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide Cinacalcet Impurity|CS-0229383

Structure of 1005450-55-4

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General Information

  • CAS No. 1005450-55-4
  • Cat. No. CS-0229383
  • Purity ≥98%
  • MDL No. MFCD18207041
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₀F₃NO
  • Molecular Weight 371.40
  • Synonym(s) N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide
  • SMILES O=C(CCC1=CC=CC(C(F)(F)F)=C1)N[C@H](C)C2=CC=CC3=C2C=CC=C3

Synthesis

  • Route1

    References

    • WO2009/2427 A2, ; Page/Page column 39 ;
  • Route2
    • (R)-1-(Naphthalen-1-yl)ethanamine Cinacalcet Impurity|CS-0214139
      3886-70-2
    • 3-(3-(Trifluoromethyl)phenyl)propanoic acid Cinacalcet Impurity|CS-0214029
      585-50-2
    • ~81%
    • (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide Cinacalcet Impurity|CS-0229383
      1005450-55-4

    References

    • Journal of Organic Chemistry, , vol. 76, # 7 p. 2187 - 2194
  • Route3
    • null|null
      1095393-72-8
    • ~99%
    • (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide Cinacalcet Impurity|CS-0229383
      1005450-55-4

    References

    • WO2009/2427 A2, ; Page/Page column 41-42 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   5.6686
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   5

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