Commercial Production
API & Intermediates Manufacturing
c-GMP Manufacturing Site 1
ADC Payload-Linker, HPAPI, API, Intermediates Process Development and Manufacturing
- Total area: ~118,403 ft2
- 4 GMP HPAPI production lines (OEB5, OEL 0.01μg/m3 ), total volume over 4,000L
- 1 GMP kilogram scale production line, 1 non-GMP kilogram scale production line
- 5 Class D clean room
- Scale up to kilograms (commercial scale）
- Multiple prep-HPLC and Lyophilizers
- Designed with maximum operation efficiency, which include negative pressure isolators to meet operation requirements of the most toxic highly toxic and highly reactive
c-GMP Manufacturing Site 2
Key RSMs, API, Intermediates, Process Development and Manufacturing
- Total area：~945,000 ft2
- Number of reactors: ~120, range from 500L-5000L
- Total reactor volume：~320,000L
- Reactions: Hydrogenation reaction, Grignard reaction, oxidation reaction, chlorination reaction, photoreaction, high temperature reaction(220°C) and deep cryogenic reaction (-80°C)
- Product types: Cardiovascular/diabetes-related APIs and intermediates
- MOC of the reactors：Glass-lining (GL), Stainless steel (SS）
