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Structure of 1012881-39-8
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2-(tert-Butyl)thiazole-5-carboxylic acid features a sterically hindered tert-butyl group that enhances solubility and stability in organic media. The electron-deficient thiazole ring facilitates efficient coupling reactions, while the carboxylic acid moiety enables direct conjugation or derivatization under standard conditions. This compound serves as a key building block in medicinal chemistry and materials science applications.
2-(tert-Butyl)thiazole-5-carboxylic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, offering a robust scaffold for C–H functionalization and transition-metal-catalyzed coupling reactions. The tert-butyl group enhances steric bulk and metabolic stability, while the carboxylic acid functionality enables direct derivatization or incorporation into peptide-like motifs. Its bench-stable nature and compatibility with standard purification methods facilitate efficient downstream processing in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: