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Structure of 101349-12-6
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2-(5-Fluoro-1H-indol-3-yl)ethan-1-ol features a fluorinated indole core linked to a primary alcohol side chain, enabling direct functionalization in medicinal chemistry. The electron-deficient indole moiety enhances metabolic stability, while the pendant hydroxyl group facilitates conjugation or derivatization under standard conditions. This scaffold integrates readily into bioactive molecules requiring targeted aromatic and polar functionalities.
2-(5-Fluoro-1H-indol-3-yl)ethan-1-ol serves as a versatile building block for the synthesis of biologically active indole derivatives. Its pendant hydroxyl group enables straightforward functionalization via etherification or oxidation, while the electron-deficient 5-fluoroindole core supports palladium-catalyzed cross-coupling reactions. The compound exhibits good bench stability and facilitates efficient purification, making it suitable for iterative medicinal chemistry campaigns and API intermediate development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H317-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P272-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: