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Structure of 1040377-08-9
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4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-ethanol is a bench-stable boronate ester featuring a pyrazole core linked to a terminal ethanol group. This structure enables efficient Suzuki-Miyaura coupling reactions under mild conditions. The tetramethyl-substituted dioxaborolane moiety enhances stability and reactivity, while the polar hydroxyl group improves solubility in common organic solvents. Ideal for constructing complex heterocyclic architectures in medicinal chemistry and materials science.
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-ethanol serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The pyrazole core provides robust heterocyclic functionality with good metabolic stability, while the pendant ethanol group offers handle for further derivatization. Bench-stable and compatible with a broad range of reaction conditions, it facilitates efficient assembly of complex molecular architectures in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: