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Structure of 1060810-15-2
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5-Bromo-2-methylisonicotinaldehyde features a bromine atom at the 5-position and a methyl group at the 2-position of the isonicotinaldehyde scaffold, delivering enhanced electron deficiency and steric profile. This configuration enables efficient coupling in cross-coupling reactions and facilitates incorporation into bioactive heterocycles. The aldehyde functionality provides direct handle for conjugation under mild conditions.
5-Bromo-2-methylisonicotinaldehyde serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient access to substituted pyridine derivatives via cross-coupling and condensation reactions. Its brominated pyridine core supports palladium-catalyzed transformations, while the aldehyde functionality facilitates imine formation and reductive amination. The methyl group enhances metabolic stability and provides a handle for further functionalization. Bench-stable and readily purified by distillation or chromatography, it functions reliably in multistep syntheses requiring orthogonal reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: