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Structure of 1093878-32-0
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This oxetane derivative features a 4-bromophenyl substituent that imparts enhanced metabolic stability and lipophilicity, making it a valuable scaffold in medicinal chemistry. The hydroxyl group enables facile derivatization and conjugation, while the oxetane ring provides favorable physicochemical properties including high polarity and reduced tendency for metabolic oxidation. This combination supports efficient incorporation into drug candidates requiring balanced solubility and membrane permeability.
3-(4-Bromophenyl)oxetan-3-ol serves as a versatile building block in medicinal chemistry, enabling direct incorporation of both brominated aromatic and oxetane functionalities. The oxetane ring imparts enhanced metabolic stability and favorable physicochemical properties, while the pendant bromide facilitates downstream cross-coupling reactions. Its bench-stable solid form and compatibility with palladium-catalyzed transformations make it ideal for constructing complex heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: