Fmoc-Arg(Me,Pbf)-OH

CAS No. 1135616-49-7
Cat. No. CS-0005659
Molecule weight662.80
Purity≥97%
MDL No.MFCD08064312

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General Information

CAS No. 1135616-49-7
Cat. No. CS-0005659
Purity ≥97%
MDL No. MFCD08064312
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₅H₄₂N₄O₇S
Molecular Weight 662.80
Synonym(s) N-α-(9-Fluorenylmethoxycarbonyl)-N-ω-methyl-N-ω'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
SMILES O=S(N/C(NC)=N/CCC[C@@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)(C4=C(C)C(C)=C(OC(C)(C5)C)C5=C4C)=O

Description

Fmoc-Arg(Me,Pbf)-OH is a protected arginine derivative designed for solid-phase peptide synthesis. The side chain bears a Pbf (para-benzylphenyl) group, offering enhanced stability and orthogonal deprotection. The Nε-methyl substitution reduces basicity and minimizes aggregation. This combination enables efficient incorporation of arginine residues with high fidelity under standard coupling conditions.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 155.42
LogP 4.95116
H_Acceptors 7
H_Donors 4
Rotatable_Bonds 10

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Arginine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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Fmoc-Arg(Me,Pbf)-OH

CAS No. 1135616-49-7

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