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Structure of 115382-35-9
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4-Acetyl-2-chlorobenzoic acid features a chlorinated benzene core bearing both acetyl and carboxylic acid functionalities. This dual-functionalized scaffold enables direct incorporation into pharmaceutical intermediates and specialty polymers. The electron-withdrawing chlorine enhances reactivity at the aromatic ring, while the acetyl group offers a handle for derivatization under mild conditions.
4-Acetyl-2-chlorobenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzimidazoles, quinolines, and other heterocyclic scaffolds. The ortho-chloro and acetyl groups provide complementary reactivity for palladium-catalyzed cross-couplings and electrophilic functionalization, while the carboxylic acid facilitates direct derivatization or salt formation. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step sequences requiring robust functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: