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Structure of 1193104-53-8
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This boronate ester features a difluoromethylpyridine core, enabling direct incorporation into cross-coupling reactions. The tetramethyl-1,3,2-dioxaborolane moiety provides enhanced stability and moisture tolerance, simplifying handling under standard conditions. Ideal for late-stage functionalization in medicinal chemistry.
2-(Difluoromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The difluoromethyl group imparts enhanced metabolic stability and modulates electronic properties, while the pinacol boronate moiety enables reliable coupling under mild conditions. This reagent exhibits excellent bench stability, tolerates diverse functional groups, and facilitates efficient construction of fluorinated heterocyclic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1760
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: