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CS-W001157 4
Total: USD 88.00

4-Chloropyridazine hydrochloride

  • CAS No. 1193386-63-8

  • Cat. No. CS-0005644
  • Molecule weight150.99
  • Purity≥97%
  • MDL No.MFCD13176698

*For research and further manufacturing use only, not for direct human use.

4-Chloropyridazine hydrochloride|CS-0005644

Structure of 1193386-63-8

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General Information

  • CAS No. 1193386-63-8
  • Cat. No. CS-0005644
  • Purity ≥97%
  • MDL No. MFCD13176698
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄Cl₂N₂
  • Molecular Weight 150.99
  • Synonym(s) 4-Chloro-pyridazineHCl
  • SMILES ClC1=CC=NN=C1.Cl

Description

4-Chloropyridazine hydrochloride is a bench-stable, moisture-tolerant heterocyclic compound featuring a chlorine atom at the 4-position of the pyridazine ring. This electron-deficient core enables direct functionalization in cross-coupling reactions and serves as a key scaffold in medicinal chemistry for targeted kinase inhibition and bioactive molecule synthesis.

Application

4-Chloropyridazine hydrochloride serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C4 position via palladium-catalyzed cross-coupling reactions. Its bench-stable, crystalline form facilitates handling and purification, while the chloro group exhibits high reactivity in Suzuki, Stille, and Negishi couplings. The hydrochloride salt enhances solubility in polar solvents, supporting efficient reaction setup in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   1.5518
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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