2,6-Dibromo-4-chloropyridine

CAS No. 1196156-59-8
Cat. No. CS-0092843
Purity≥97%
MDL No.MFCD13189630

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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Description

2,6-Dibromo-4-chloropyridine features a highly electron-deficient pyridine core functionalized with bromo and chloro substituents at key positions. This arrangement enables selective cross-coupling reactions under mild conditions, facilitating efficient access to complex heterocyclic architectures in medicinal chemistry and materials science applications.

Application

2,6-Dibromo-4-chloropyridine serves as a versatile building block in heterocyclic synthesis, enabling regioselective functionalization at the 2- and 6-positions via palladium-catalyzed cross-coupling. Its orthogonal halogen reactivity profile facilitates sequential transformations, while the chloro group offers compatibility with nucleophilic substitution. The compound exhibits good bench stability and is readily purified by crystallization, making it well-suited for iterative synthesis of complex pyridine-based scaffolds.

General Information

CAS No. 1196156-59-8
Cat. No. CS-0092843
Purity ≥97%
MDL No. MFCD13189630
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₂Br₂ClN
Molecular Weight 271.34
Synonym(s) None
SMILES ClC1=CC(Br)=NC(Br)=C1

Computational Chemistry Data

TPSA 12.89
LogP 3.26
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2,6-Dibromo-4-chloropyridine

CAS No. 1196156-59-8

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