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CS-W001157 4
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Methyl 6-chloro-5-(hydroxymethyl)picolinate

  • CAS No. 1205671-72-2

  • Cat. No. CS-0197753
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 6-chloro-5-(hydroxymethyl)picolinate|CS-0197753

Structure of 1205671-72-2

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General Information

  • CAS No. 1205671-72-2
  • Cat. No. CS-0197753
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈ClNO₃
  • Molecular Weight 201.61
  • Synonym(s) None
  • SMILES O=C(OC)C1=NC(Cl)=C(C=C1)CO

Description

Methyl 6-chloro-5-(hydroxymethyl)picolinate features a strategically positioned chloro group and a hydroxymethyl side chain on the picolinate scaffold, enabling selective functionalization in synthetic routes. This bench-stable derivative integrates readily into complex molecular architectures, offering enhanced solubility and compatibility in transition metal-catalyzed transformations.

Application

Methyl 6-chloro-5-(hydroxymethyl)picolinate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized heterocyclic scaffolds. The hydroxymethyl group facilitates selective derivatization via oxidation, protection, or substitution reactions, while the chloro and ester functionalities support further transformations such as nucleophilic displacement or cross-coupling. Its bench-stable nature and compatibility with standard purification methods make it well-suited for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   59.42
  • LogP   1.0139
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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