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Structure of 1206250-40-9
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Methyl 4-bromopyrimidine-2-carboxylate features a bromine atom at the 4-position of a pyrimidine core, enabling selective functionalization in cross-coupling reactions. The ester group provides enhanced solubility and reactivity under standard conditions, while the electron-deficient heterocycle facilitates nucleophilic substitution. This compound serves as a key intermediate in synthesizing bioactive pyrimidine derivatives and pharmaceutical scaffolds.
Methyl 4-bromopyrimidine-2-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. The bromine at the 4-position facilitates palladium-catalyzed cross-coupling reactions, while the ester group supports selective transformations and derivatization. Its bench-stable nature and compatibility with diverse functional groups make it ideal for iterative synthesis workflows targeting heterocyclic APIs and kinase inhibitors.
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GHS No : GHS07,GHS05
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Signal Word : Danger
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: