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N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-N-methyl-D-serine

  • CAS No. 1210833-53-6

  • Cat. No. CS-0173334
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-N-methyl-D-serine|CS-0173334

Structure of 1210833-53-6

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Description

Fmoc-O-tert-butyl-N-methyl-D-serine is a chiral, protected D-amino acid derivative designed for peptide synthesis. The fluoren-9-ylmethoxycarbonyl (Fmoc) group enables efficient orthogonal protection, while the tert-butyl ester provides stability under basic conditions. This derivative integrates seamlessly into solid-phase workflows, offering reliable coupling and minimal epimerization.

Application

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-N-methyl-D-serine serves as a protected D-serine building block for peptide synthesis, enabling efficient incorporation of D-amino acids into peptidomimetics. The Fmoc group provides orthogonal protection for the amine, while the tert-butyl ester offers stable protection of the hydroxyl that can be selectively removed under mild acidic conditions. Its compatibility with standard coupling protocols and bench stability make it ideal for solid-phase and solution-phase synthesis workflows.

General Information

  • CAS No. 1210833-53-6
  • Cat. No. CS-0173334
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₂₇NO₅
  • Molecular Weight 397.46
  • Synonym(s) Fmoc-N-Me-D-Ser(tBu)-OH
  • SMILES O=C(O)[C@@H](COC(C)(C)C)N(C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C

Computational Chemistry Data

  • TPSA   76.07
  • LogP   4.1356
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   6

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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