(R)-Morpholine-2-carboxylic acid

CAS No. 1212396-52-5
Cat. No. CS-0102851
Purity≥97%
MDL No.MFCD11052514

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FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(R)-Morpholine-2-carboxylic acid|CS-0102851

Structure of 1212396-52-5

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Description

(R)-Morpholine-2-carboxylic acid is a chiral building block featuring a rigid, electron-rich morpholine ring fused to a carboxylic acid at the 2-position. This configuration enables high stereoselectivity in peptide synthesis and bioactive molecule construction. The compound exhibits excellent solubility in polar solvents and stability under standard bench conditions, facilitating integration into diverse synthetic workflows.

Application

(R)-Morpholine-2-carboxylic acid serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through established coupling and cyclization protocols. Its well-defined stereochemistry and stability under standard reaction conditions facilitate reliable incorporation into peptidomimetics and heterocyclic scaffolds. The carboxylic acid functionality supports direct derivatization or activation for amide bond formation, while the morpholine ring provides favorable solubility and metabolic profile attributes.

General Information

CAS No. 1212396-52-5
Cat. No. CS-0102851
Purity ≥97%
MDL No. MFCD11052514
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₉NO₃
Molecular Weight 131.13
Synonym(s) (R)-Morpholine-2-carboxylicacid
SMILES O=C([C@H]1CNCCO1)O

Computational Chemistry Data

TPSA 58.56
LogP -0.9406
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Morpholine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-Morpholine-2-carboxylic acid

CAS No. 1212396-52-5

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