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CS-W001157 4
Total: USD 88.00

Propargyl-PEG1-NH2

  • CAS No. 122116-12-5

  • Cat. No. CS-0063716
  • Purity≥96%
  • MDL No.MFCD16713446
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Propargyl-PEG1-NH2|CS-0063716

Structure of 122116-12-5

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Description

Propargyl-PEG1-NH2 features a reactive alkyne handle flanked by a short, hydrophilic PEG spacer and a primary amine group. This bifunctional architecture enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) while maintaining solubility in aqueous environments. Ideal for bioconjugation workflows requiring site-specific labeling and minimal steric interference.

Application

Propargyl-PEG1-NH₂ serves as a versatile bifunctional building block for click chemistry and bioconjugation, combining a terminal alkyne for CuAAC reactions with a primary amine for amide coupling. Its short PEG spacer enhances solubility and reduces steric hindrance, enabling efficient conjugation in peptide, protein, and oligonucleotide modifications. The compound exhibits excellent bench stability and is readily purified by standard chromatographic methods, making it ideal for routine synthesis and high-throughput applications.

General Information

  • CAS No. 122116-12-5
  • Cat. No. CS-0063716
  • Purity ≥96%
  • MDL No. MFCD16713446
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉NO
  • Molecular Weight 99.13
  • Synonym(s) None
  • SMILES C#CCOCCN

Computational Chemistry Data

  • TPSA   35.25
  • LogP   -0.4051
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 2734
Class : 8 (3)
Packing Group :
Hazard Statements : H226-H314
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501

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