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Structure of 122116-12-5
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Propargyl-PEG1-NH2 features a reactive alkyne handle flanked by a short, hydrophilic PEG spacer and a primary amine group. This bifunctional architecture enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) while maintaining solubility in aqueous environments. Ideal for bioconjugation workflows requiring site-specific labeling and minimal steric interference.
Propargyl-PEG1-NH₂ serves as a versatile bifunctional building block for click chemistry and bioconjugation, combining a terminal alkyne for CuAAC reactions with a primary amine for amide coupling. Its short PEG spacer enhances solubility and reduces steric hindrance, enabling efficient conjugation in peptide, protein, and oligonucleotide modifications. The compound exhibits excellent bench stability and is readily purified by standard chromatographic methods, making it ideal for routine synthesis and high-throughput applications.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 2734
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Class : 8 (3)
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Packing Group : Ⅱ
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Hazard Statements : H226-H314
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: