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CS-W001157 4
Total: USD 88.00

(3-(Trifluoromethyl)pyridin-4-yl)methanol

  • CAS No. 1227598-69-7

  • Cat. No. CS-0188048
  • Molecule weight177.12
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3-(Trifluoromethyl)pyridin-4-yl)methanol|CS-0188048

Structure of 1227598-69-7

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General Information

  • CAS No. 1227598-69-7
  • Cat. No. CS-0188048
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆F₃NO
  • Molecular Weight 177.12
  • Synonym(s) 3-(Trifluoromethyl)pyridine-4-methanol
  • SMILES C1=C(CO)C(=CN=C1)C(F)(F)F

Description

This trifluoromethylpyridine derivative features a reactive primary alcohol group positioned ortho to a strongly electron-withdrawing trifluoromethylpyridine moiety. The combination imparts enhanced solubility and stability under standard conditions, enabling efficient incorporation into pharmaceutical intermediates and functional materials through straightforward derivatization.

Application

(3-(Trifluoromethyl)pyridin-4-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient incorporation of a polar trifluoromethylpyridine motif. The primary alcohol functionality facilitates straightforward derivatization via esterification, ether formation, or oxidation to the carboxylic acid. Its bench-stable nature and compatibility with standard coupling reactions make it a practical choice for constructing bioactive heterocyclic scaffolds and functionalizing APIs.

Safety Information

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GHS Pictogram :
GHS No : GHS03,GHS05,GHS09
Signal Word : Danger
UN#: 1479
Class : 5.1
Packing Group : Ⅲ
Hazard Statements : H272-H314-H410
Precautionary Statements : P210-P220-P260-P264-P273-P280-P301+P330+P331-P304+P340-P363-P370+P378-P391-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.5927
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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