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Structure of 1240587-95-4
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Tert-butyl (S)-3-(trifluoromethyl)piperazine-1-carboxylate features a chiral piperazine core with a strongly electron-withdrawing trifluoromethyl group, enhancing stability and modulating basicity. This bench-stable, moisture-tolerant building block integrates readily into medicinal chemistry campaigns requiring fluorinated heterocycles.
Tert-butyl (S)-3-(trifluoromethyl)piperazine-1-carboxylate serves as a stable, bench-ready chiral building block for medicinal chemistry and process development. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the piperazine core enables versatile functionalization in late-stage diversification. The tert-butyl carbamate protects the amine under standard conditions, facilitating purification and compatibility with diverse coupling reactions. This compound functions effectively in transition-metal-catalyzed cross-couplings, nucleophilic substitutions, and heterocycle assembly workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: