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Structure of 1243143-45-4
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This boronate ester features a trifluoromethyl-substituted phenol scaffold, combining enhanced stability with high reactivity in Suzuki-Miyaura cross-coupling. The tetramethylboronate moiety enables efficient palladium-catalyzed transformations under standard conditions, delivering aryl-trifluoromethyl products with minimal decomposition.
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)phenol serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the pinacol boronate moiety offers excellent bench stability, ease of handling, and compatibility with diverse reaction conditions. It facilitates efficient construction of biaryl scaffolds in medicinal chemistry and materials science workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: