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CS-W001157 4
Total: USD 88.00

B-1H-Pyrrolo[2,3-b]pyridin-4-ylboronic acid

  • CAS No. 1246761-84-1

  • Cat. No. CS-0030591
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

B-1H-Pyrrolo[2,3-b]pyridin-4-ylboronic acid|CS-0030591

Structure of 1246761-84-1

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Description

B-1H-Pyrrolo[2,3-b]pyridin-4-ylboronic acid features a heteroaryl boronic acid moiety integrated into a fused pyrrolopyridine scaffold. This configuration imparts enhanced stability and reactivity in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The electron-deficient nature of the ring system promotes selective coupling with diverse aryl halides.

Application

B-1H-Pyrrolo[2,3-b]pyridin-4-ylboronic acid serves as a versatile building block for constructing biologically relevant heterocyclic scaffolds. Its boronic acid functionality enables efficient Suzuki-Miyaura cross-coupling reactions under mild conditions, facilitating the synthesis of complex arylated derivatives with high regioselectivity. The compound exhibits good bench stability and compatibility with diverse functional groups, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

General Information

  • CAS No. 1246761-84-1
  • Cat. No. CS-0030591
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇BN₂O₂
  • Molecular Weight 161.95
  • Synonym(s) 1H-Pyrrolo[2,3-B]pyridin-4-ylboronic acid
  • SMILES OB(C1=C2C(NC=C2)=NC=C1)O

Computational Chemistry Data

  • TPSA   69.14
  • LogP   -0.7573
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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