3-Bromo-5-methylpyrazin-2(1H)-one

CAS No. 1260810-61-4
Cat. No. CS-0188073
Molecule weight189.01
Purity≥98%
MDL No.MFCD13193675

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Bromo-5-methylpyrazin-2(1H)-one|CS-0188073

Structure of 1260810-61-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1260810-61-4
Cat. No. CS-0188073
Purity ≥98%
MDL No. MFCD13193675
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₅BrN₂O
Molecular Weight 189.01
Synonym(s) 3-Bromo-5-methyl-2(1H)-pyrazinone
SMILES O=C1NC=C(N=C1Br)C

Description

3-Bromo-5-methylpyrazin-2(1H)-one features a brominated pyrazinone core with a methyl group at the 5-position, offering a reactive site for cross-coupling and a sterically accessible framework for derivatization. This bench-stable heterocycle integrates readily into complex molecular architectures under standard conditions.

Application

3-Bromo-5-methylpyrazin-2(1H)-one serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromine substituent. The pyrazinone core provides hydrogen-bonding capability and metabolic stability, while the methyl group enhances lipophilicity and electronic modulation. Bench-stable and amenable to purification by recrystallization, it facilitates efficient synthesis of heterocyclic scaffolds relevant to kinase inhibitors and antimicrobial agents.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 45.75
LogP 0.84082
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Other aliphatic heterocycles compounds

Key Words

3-Bromo-5-methylpyrazin-2(1H)-one sigma3-Bromo-5-methylpyrazin-2(1H)-one manufacturer3-Bromo-5-methylpyrazin-2(1H)-one price3-Bromo-5-methylpyrazin-2(1H)-one structure3-Bromo-5-methylpyrazin-2(1H)-one SDSbuy 3-Bromo-5-methylpyrazin-2(1H)-one3-Bromo-5-methylpyrazin-2(1H)-one supplier3-Bromo-5-methylpyrazin-2(1H)-one uses3-Bromo-5-methylpyrazin-2(1H)-one molecular weightprice of 3-Bromo-5-methylpyrazin-2(1H)-one3-Bromo-5-methylpyrazin-2(1H)-one chemical name formula of 3-Bromo-5-methylpyrazin-2(1H)-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

3-Bromo-5-methylpyrazin-2(1H)-one

CAS No. 1260810-61-4

Recommended Products