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CS-W001157 4
Total: USD 88.00

Losartan impurity 18

  • CAS No. 133909-99-6

  • Cat. No. CS-0089264
  • Molecule weight665.24
  • Purity≥98%
  • MDL No.MFCD09028113

*For research and further manufacturing use only, not for direct human use.

Losartan impurity 18|CS-0089264

Structure of 133909-99-6

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General Information

  • CAS No. 133909-99-6
  • Cat. No. CS-0089264
  • Purity ≥98%
  • MDL No. MFCD09028113
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₁H₃₇ClN₆O
  • Molecular Weight 665.24
  • Synonym(s) Trithyl Losartan
  • SMILES ClC=1N=C(N(C1CO)CC2=CC=C(C=C2)C3=CC=CC=C3C=4N=NN(N4)C(C=5C=CC=CC5)(C=6C=CC=CC6)C=7C=CC=CC7)CCCC

Synthesis

  • Route1

    References

    • MEDICHEM, S.A. Patent: WO2007/20533 A2, 2007 ; Location in patent: Page/Page column 11-12 ;
  • Route2
    • null|null
      109-69-3
    • Losartan impurity 1|CS-0786772
      133910-00-6
    • ~73%
    • Losartan impurity 18|CS-0089264
      133909-99-6

    References

    • Lo; Young S.; Rossano; Lucius T. Patent: US5130439 A1, 1992 ; US 5130439 A
  • Route3
    • Losartan impurity 1|CS-0786772
      133910-00-6
    • null|null
      99281-96-6
    • ~38%
    • null|null
      1370339-88-0
    • Losartan impurity 18|CS-0089264
      133909-99-6

    References

    • European Journal of Medicinal Chemistry, , vol. 50, p. 90 - 101

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   81.65
  • LogP   8.5804
  • H_Acceptors   7
  • H_Donors   1
  • Rotatable_Bonds   12

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