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Structure of 1353012-00-6
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N3-PEG4-C2-Pfp ester features a reactive pentafluorophenyl ester group for efficient amide bond formation, paired with a short PEG4 spacer and a terminal azide for bioorthogonal conjugation. This bifunctional reagent enables site-specific labeling of proteins and biomolecules under mild conditions, combining excellent solubility with stability in aqueous environments.
N3-PEG4-C2-Pfp ester serves as a versatile, bifunctional linker for site-specific conjugation in synthetic chemistry. The azide group enables efficient copper-free click reactions with alkynes, while the pentafluorophenyl (Pfp) ester readily reacts with primary amines under mild conditions. The PEG4 spacer provides enhanced solubility and reduced aggregation, making it ideal for bioconjugation workflows. This reagent offers excellent stability, ease of purification, and compatibility with diverse functional groups in peptide, oligonucleotide, and small-molecule modifications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: