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Structure of 1354952-28-5
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This bicyclic scaffold features a constrained heterocyclic core with strategic oxygen and nitrogen atoms, enabling precise spatial orientation in synthetic intermediates. The hydrochloride salt enhances solubility and stability under standard conditions, facilitating use in medicinal chemistry workflows.
2-Oxa-5-azabicyclo[4.1.0]heptane hydrochloride serves as a rigid, conformationally constrained heterocyclic building block for medicinal chemistry applications. Its fused bicyclic structure imparts excellent metabolic stability and defined spatial orientation, enabling precise bioactive conformation presentation. The molecule exhibits robust bench stability, tolerates diverse functional groups, and participates reliably in nucleophilic substitution and coupling reactions, facilitating rapid access to complex scaffolds in API discovery campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: