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Structure of 1396215-84-1
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This oxetane-bearing boronate ester delivers enhanced stability and reactivity in Suzuki-Miyaura coupling, where the oxetan-3-yl group enables efficient C–C bond formation under mild conditions. Its bench-stable, moisture-tolerant structure simplifies handling in complex synthetic sequences.
4,4,5,5-Tetramethyl-2-(oxetan-3-yl)-1,3,2-dioxaborolane serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. Its oxetanyl group provides enhanced metabolic stability and improved solubility in medicinal chemistry applications. The tetramethyl substitution enhances reactivity and minimizes protodeboronation, enabling high-yielding couplings under standard conditions. This reagent facilitates efficient C–C bond formation with aryl, vinyl, and heteroaryl halides, offering excellent functional group tolerance and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: