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CS-W001157 4
Total: USD 88.00

(R)-Efavirenz

  • CAS No. 154801-74-8

  • Cat. No. CS-0092179
  • Molecule weight315.67
  • Purity≥98%
  • MDL No.MFCD18252393

*For research and further manufacturing use only, not for direct human use.

(R)-Efavirenz|CS-0092179

Structure of 154801-74-8

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General Information

  • CAS No. 154801-74-8
  • Cat. No. CS-0092179
  • Purity ≥98%
  • MDL No. MFCD18252393
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₉ClF₃NO₂
  • Molecular Weight 315.67
  • Synonym(s) (R)-DMP 266; (R)-EFV; (R)-L-743726
  • SMILES FC(F)(F)[C@]1(C2=CC(Cl)=CC=C2NC(O1)=O)C#CC3CC3

Synthesis

  • Route1
    • null|null
      1381993-90-3
    • ~0%
    • (R)-Efavirenz|CS-0092179
      154801-74-8
    • In-stock
      Efavirenz|CS-2154
      154598-52-4

    References

    • LONZA LTD; LONZA GUANGZHOU RESEARCH AND DEVELOPMENT CENTER LTD; DAI, Danmei; LONG, Xiangtian; LUO, Bing; KULESZA, Anna; REICHWAGEN, Jens; GUO, Yanming Patent: WO2012/97510 A1, 2012 ; Location in patent: Page/Page column 60-61 ;
  • Route2
    • null|null
      75-44-5
    • null|null
      1236354-27-0
    • ~98%
    • (R)-Efavirenz|CS-0092179
      154801-74-8

    References

    • Lonza Ltd Patent: EP2447247 A1, 2012 ; Location in patent: Page/Page column 11-12 ;
  • Route3
    • null|null
      32315-10-9
    • (S)-2-(2-Amino-5-chloro-phenyl)-4-cyclopropyl-1,1,1-trifluoro-but-3-yn-2-ol|CS-0341179
      209414-27-7
    • ~91%
    • (R)-Efavirenz|CS-0092179
      154801-74-8

    References

    • Lonza Ltd Patent: EP2447247 A1, 2012 ; Location in patent: Page/Page column 9 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   4.0731
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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