Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-Bromo-3,3-dimethyl-2,3-dihydro-1H-indole

  • CAS No. 158326-85-3

  • Cat. No. CS-0050284
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD11847807

*For research and further manufacturing use only, not for direct human use.

6-Bromo-3,3-dimethyl-2,3-dihydro-1H-indole|CS-0050284

Structure of 158326-85-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 158326-85-3
  • Cat. No. CS-0050284
  • Purity ≥97%
  • MDL No. MFCD11847807
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂BrN
  • Molecular Weight None
  • Synonym(s) 6-broMo-3,3-diMethylindoline
  • SMILES CC1(C)CNC2=CC(Br)=CC=C12

Description

6-Bromo-3,3-dimethyl-2,3-dihydro-1H-indole is a sterically hindered bromoindoline derivative featuring a bench-stable, electron-deficient heterocyclic core. This compound integrates readily into cross-coupling reactions and serves as a key building block for functionalized indole scaffolds in medicinal chemistry and materials science.

Application

6-Bromo-3,3-dimethyl-2,3-dihydro-1H-indole serves as a versatile building block for the synthesis of biologically relevant indole derivatives. The bromine at the 6-position enables palladium-catalyzed cross-coupling reactions, while the 3,3-dimethyl substitution enhances stability and facilitates purification. This scaffold functions effectively in the construction of heterocyclic frameworks and drug-like molecules, offering excellent functional group tolerance and predictable reactivity in standard synthetic workflows.

Synthesis

  • Route1

    References

    • Eisai Co., Ltd. Patent: US2002/19531 A1, 2002 ; US 20020019531 A1
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 39, # 1 p. 304 - 313
  • Route3
    • null|null
      65617-24-5
    • ~%
    • In-stock
      6-Bromo-3,3-dimethyl-2,3-dihydro-1H-indole|CS-0050284
      158326-85-3

    References

    • Journal of Medicinal Chemistry, , vol. 39, # 1 p. 304 - 313

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   12.03
  • LogP   3.1522
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 158326-85-3 sigma158326-85-3 manufacturer158326-85-3 price158326-85-3 structure158326-85-3 SDSbuy 158326-85-3158326-85-3 supplier158326-85-3 uses158326-85-3 molecular weightprice of 158326-85-3158326-85-3 chemical name formula of 158326-85-3
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label