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Structure of 15953-45-4
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5-Chloro-3-methyl-1H-pyrazole is a bench-stable heterocyclic scaffold featuring a chlorinated pyrazole core with a methyl substituent at the 3-position. This electron-deficient ring system integrates readily into medicinal chemistry libraries, offering enhanced metabolic stability and enabling direct coupling in cross-coupling reactions.
5-Chloro-3-methyl-1H-pyrazole serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted pyrazole scaffolds via cross-coupling and nucleophilic substitution reactions. Its chlorine at C5 provides a reliable handle for palladium-catalyzed functionalization, while the methyl group at C3 enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability, ease of purification, and compatibility with diverse reaction conditions, making it ideal for high-throughput synthesis of bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: