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CS-W001157 4
Total: USD 88.00

2-Cyclohexyl-4-methylphenol

  • CAS No. 1596-09-4

  • Cat. No. CS-M0186
  • Molecule weight190.29
  • Purity≥98%
  • MDL No.MFCD00035858

*For research and further manufacturing use only, not for direct human use.

2-Cyclohexyl-4-methylphenol|CS-M0186

Structure of 1596-09-4

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General Information

  • CAS No. 1596-09-4
  • Cat. No. CS-M0186
  • Purity ≥98%
  • MDL No. MFCD00035858
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₈O
  • Molecular Weight 190.29
  • Synonym(s) 4-Methyl-2-cyclohexylphenol
  • SMILES OC1=C(C2CCCCC2)C=C(C)C=C1

Description

2-Cyclohexyl-4-methylphenol offers a sterically hindered phenolic architecture that enhances oxidative stability in polymer systems. This compound integrates readily into resin formulations, where its hydrophobic cyclohexyl and methyl substituents provide robust resistance to thermal degradation. The para-methyl group optimizes electron density at the phenolic oxygen, enabling efficient radical scavenging under standard processing conditions.

Application

2-Cyclohexyl-4-methylphenol serves as a valuable building block in the synthesis of functionalized aromatic scaffolds, leveraging its ortho-substituted phenolic functionality for downstream derivatization. The cyclohexyl and methyl groups provide steric and electronic modulation, enhancing stability and solubility in organic media. Its bench-stable nature and compatibility with standard coupling and oxidation protocols facilitate efficient incorporation into complex molecular architectures relevant to agrochemical and pharmaceutical research.

Synthesis

  • Route1
    • null|null
      106-44-5
    • ~92%
    • In-stock
      2-Cyclohexyl-4-methylphenol|CS-M0186
      1596-09-4

    References

    • Bayer Aktiengesellschaft Patent: US4990687 A1, 1991 ;
  • Route2
    • null|null
      106-44-5
    • In-stock
      1-Cyclohexanol|CS-0017198
      108-93-0
    • ~85%
    • In-stock
      2-Cyclohexyl-4-methylphenol|CS-M0186
      1596-09-4

    References

    • Yadav, Ganapati D.; Pathre, Ganesh S. Synthetic Communications, 2008 , vol. 38, # 15 p. 2684 - 2691
  • Route3
    • null|null
      106-44-5
    • null|null
      110-83-8
    • ~%
    • null|null
      1791-41-9
    • In-stock
      2-Cyclohexyl-4-methylphenol|CS-M0186
      1596-09-4

    References

    • Applied Catalysis A: General, , vol. 472, p. 184 - 190

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   3.74832
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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