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Structure of 160481-43-6
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(Iodoethynyl)triisopropylsilane features a terminal alkyne anchored by a robust triisopropylsilyl group, enabling stable coupling in transition-metal-catalyzed reactions. This bench-stable reagent facilitates efficient C–C bond formation under mild conditions, particularly in Sonogashira and copper-free click chemistry applications.
(Iodoethynyl)triisopropylsilane serves as a stable, bench-ready building block for Sonogashira coupling reactions. Its triisopropylsilyl group provides enhanced steric protection and improved solubility, facilitating efficient cross-coupling with aryl and vinyl halides under mild conditions. The terminal alkyne functionality enables straightforward access to conjugated enynes and functionalized alkynyl scaffolds, making it a reliable reagent for the synthesis of complex molecular architectures in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 2924
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Class : 3,8
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Packing Group : Ⅲ
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Hazard Statements : H225-H302-H312-H315-H318-H332-H335
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Precautionary Statements : P210-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: