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(S)-Methyl piperidine-3-carboxylate hydrochloride

  • CAS No. 164323-84-6

  • Cat. No. CS-M2670
  • Molecule weight179.64
  • Purity≥97%
  • MDL No.MFCD09271813

*For research and further manufacturing use only, not for direct human use.

(S)-Methyl piperidine-3-carboxylate hydrochloride|CS-M2670

Structure of 164323-84-6

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General Information

  • CAS No. 164323-84-6
  • Cat. No. CS-M2670
  • Purity ≥97%
  • MDL No. MFCD09271813
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClNO₂
  • Molecular Weight 179.64
  • Synonym(s) (S)-3-METHYL PIPERIDINE CARBOXYLATE HYDROCHLORIDE
  • SMILES O=C(OC)[C@@H]1CNCCC1.Cl

Description

(S)-Methyl piperidine-3-carboxylate hydrochloride is a chiral building block featuring a stereochemically defined piperidine core and a methyl ester group. This bench-stable salt delivers high diastereoselectivity in asymmetric synthesis, particularly in the construction of bioactive alkaloids and pharmaceutical intermediates. The protonated nitrogen enhances solubility and facilitates downstream functionalization under mild conditions.

Application

(S)-Methyl piperidine-3-carboxylate hydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to bioactive piperidine derivatives. Its stable, crystalline form facilitates handling and purification, while the protected amine and ester functionalities offer orthogonal reactivity for late-stage functionalization. The stereochemical integrity supports consistent outcomes in asymmetric synthesis, making it well-suited for scaffold diversification in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   0.5808
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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