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Structure of 16492-28-7
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2,6-Dichloropyrimidine-4-carboxylic acid features a rigid pyrimidine core bearing two chlorine substituents at the 2 and 6 positions and a carboxylic acid group at the 4 position. This electronic configuration imparts strong electron-withdrawing character, enabling efficient coupling reactions in medicinal chemistry. The compound serves as a key scaffold for synthesizing bioactive heterocycles and exhibits stability under standard reaction conditions.
2,6-Dichloropyrimidine-4-carboxylic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis. Its dichloro substitution pattern enables selective functionalization at C2 and C6 positions, while the carboxylic acid group facilitates amidation, esterification, and metal-catalyzed coupling reactions. The molecule exhibits bench stability and compatibility with common protecting group strategies, making it well-suited for multi-step synthetic sequences involving heterocyclic scaffold elaboration.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: