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Structure of 172163-62-1
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7-Iodo-7-deaza-2'-deoxyguanosine features a iodinated 7-deazaguanine core paired with a deoxyribose sugar, enabling site-specific incorporation into oligonucleotides. This analog delivers enhanced stability and facilitates efficient conjugation via click chemistry, making it ideal for probing DNA structure and function in biochemical assays.
7-Iodo-7-deaza-2'-deoxyguanosine serves as a versatile building block for the synthesis of modified nucleosides and oligonucleotides. The iodine substituent at the C7 position enables efficient palladium-catalyzed cross-coupling reactions, facilitating site-specific conjugation or incorporation into DNA/RNA scaffolds. Its 7-deaza modification enhances stability and reduces undesired side reactivity compared to natural guanosine analogs. The 2'-deoxy configuration ensures compatibility with standard phosphoramidite chemistry and solid-phase synthesis workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: