2-Bromoimidazo[1,2-a]pyridine-7-carboxylic acid

CAS No. 1784089-67-3
Cat. No. CS-0102087
Purity≥97%
MDL No.None

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2-Bromoimidazo[1,2-a]pyridine-7-carboxylic acid|CS-0102087

Structure of 1784089-67-3

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Description

This imidazopyridine carboxylic acid features a brominated heterocyclic core that enables direct functionalization in cross-coupling reactions. The electron-deficient pyridine ring and pendant carboxylic acid group facilitate integration into bioactive scaffolds, while the bench-stable structure supports reliable handling under standard conditions.

Application

2-Bromoimidazo[1,2-a]pyridine-7-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient construction of imidazo[1,2-a]pyridine scaffolds through palladium-catalyzed cross-coupling reactions. The carboxylic acid group facilitates derivatization via amide bond formation, while the bromine atom provides a reliable handle for further functionalization. Its bench-stable solid form and compatibility with standard synthetic protocols make it well-suited for modular synthesis of bioactive heterocycles.

General Information

CAS No. 1784089-67-3
Cat. No. CS-0102087
Purity ≥97%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₅BrN₂O₂
Molecular Weight 241.04
Synonym(s) None
SMILES O=C(O)C1=CC2=NC(Br)=CN2C=C1

Computational Chemistry Data

TPSA 54.6
LogP 1.795
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2-Bromoimidazo[1,2-a]pyridine-7-carboxylic acid

CAS No. 1784089-67-3

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