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Structure of 1823349-88-7
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1-Cyclopropyl-1H-pyrazole-3-carbaldehyde features a cyclopropyl group attached to the pyrazole ring, enhancing metabolic stability and lipophilicity. The aldehyde functionality enables direct coupling in Ugi or Passerini reactions, while the electron-deficient pyrazole core supports efficient transition metal catalysis. This scaffold integrates readily into bioactive heterocycles for medicinal chemistry applications.
1-Cyclopropyl-1H-pyrazole-3-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrazole-based heterocycles via standard condensation and coupling reactions. The aldehyde functionality facilitates rapid derivatization, including reductive amination and Wittig-type transformations, while the cyclopropyl group enhances metabolic stability and modulates lipophilicity. Bench-stable and compatible with common reaction conditions, it functions effectively in multi-step syntheses of bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: